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Genotoxicity assessment of the antimalarial compound artesunate in somatic cells of mice
(Pergamon-Elsevier B.V. Ltd, 2011-06-01)
Artesunate is a derivate of artemisinin that is both an antimalarial agent and acts cytotoxically on tumor cells. Despite its therapeutic use, its in vivo genotoxic potential has still not been evaluated. This study, ...
Genotoxicity assessment of the antimalarial compound artesunate in somatic cells of mice
(Pergamon-Elsevier B.V. Ltd, 2011-06-01)
Artesunate is a derivate of artemisinin that is both an antimalarial agent and acts cytotoxically on tumor cells. Despite its therapeutic use, its in vivo genotoxic potential has still not been evaluated. This study, ...
Genotoxicity assessment of the antimalarial compound artesunate in somatic cells of mice
(Elsevier B.V., 2011-06-01)
Artesunate is a derivate of artemisinin that is both an antimalarial agent and acts cytotoxically on tumor cells. Despite its therapeutic use, its in vivo genotoxic potential has still not been evaluated. This study, ...
Genotoxicity assessment of the antimalarial compound artesunate in somatic cells of mice
(Pergamon-Elsevier B.V. Ltd, 2014)
Artemether and artesunate show the highest efficacies in rescuing mice with late-stage cerebral malaria and rapidly decrease leukocyte accumulation in the brain
(American Society for Microbiology, 2019)
Effects of artesunate against Trypanosma cruzi
(Academic Press Inc Elsevier Science, 2015-09)
Therapy against Trypanosma cruzi relies on only two chemically relatednitro-derivative drugs, benznidazole and nifurtimox, both limited by poorefficacy and toxicity. It is suspected that with prolonged usage of these drugs, ...
In vitro action of antiparasitic drugs, especially artesunate, against Toxoplasma gondii
(SOC BRASILEIRA MEDICINA TROPICALBRASILIA, 2012)
Introduction: Toxoplasmosis is usually a benign infection, except in the event of ocular, central nervous system (CNS), or congenital disease and particularly when the patient is immunocompromised. Treatment consists of ...
Genotoxic evaluation of the antimalarial drugs artemisinin and artesunate in human HepG2 cells and effects on CASP3 and SOD1 gene expressions
(2013-07-24)
The malaria treatment recommended by the World Health Organization involves medicines derived from artemisinin, an active compound extracted from the plant Artemisia annua, and some of its derivatives, such as artesunate. ...
Genotoxic evaluation of the antimalarial drugs artemisinin and artesunate in human HepG2 cells and effects on CASP3 and SOD1 gene expressions
(2013-07-24)
The malaria treatment recommended by the World Health Organization involves medicines derived from artemisinin, an active compound extracted from the plant Artemisia annua, and some of its derivatives, such as artesunate. ...