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A roadmap to engineering antiviral natural products synthesis in microbes
Natural products continue to be the inspirations for us to
discover and acquire new drugs. The seemingly unstoppable
viruses have kept records high to threaten human health and
well-being. The diversity and complexity ...
Antivirals for COVID-19: A critical review
No specific drugs have been approved for coronavirus disease 2019 (COVID-19) to date as the development of
antivirals usually requires time. Therefore, assessment and use of currently available antiviral drugs is critical ...
Plant-derived antivirals against hepatitis c virus infection
(Biomed Central Ltd, 2018-02-13)
Hepatitis C virus (HCV) infection is a worldwide public health burden and it is estimated that 185 million people are or have previously been infected worldwide. There is no effective vaccine for prevention of HCV infection; ...
Propolis antiviral and immunomodulatory activity: A review and perspectives for COVID-19 treatment
(2021-01-01)
Objectives Viral outbreaks are a frequent concern for humans. A great variety of drugs has been used to treat viral diseases, which are not always safe and effective and may induce adverse effects, indicating the need for ...
Genetic lesions of type i interferon signalling in human antiviral immunity
The concept that type I interferons (IFN-I) are essential to antiviral immunity
derives from studies on animal models and cell lines. Virtually all pathogenic
viruses have evolved countermeasures to IFN-I restriction, ...
Future antiviral surfaces: Lessons from COVID-19 pandemic
It is an urgent priority for advanced materials researchers to help find solutions
to eliminate the COVID-19 pandemic. The transmission of the SARS-CoV-2 coronavirus
is majorly through touching the contaminated surfaces ...