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        Antivenoms for Snakebite Envenomings 

        Gutiérrez, José María; León Montero, Guillermo; Lomonte, Bruno; Angulo Ugalde, Yamileth (2011-10)
        Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming. Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a single or several medically-relevant snake ...

        Antivenoms for Snakebite Envenomings 

        Gutiérrez, José María; León Montero, Guillermo; Lomonte, Bruno; Angulo Ugalde, Yamileth (2011-10)
        Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming. Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a single or several medically-relevant snake ...

        Second generation snake antivenomics: Comparing immunoaffinity and immunodepletion protocols 

        Pla Ferrer, Davinia; Gutiérrez, José María; Calvete Chornet, Juan José (2012-09-15)
        A second generation antivenomics protocol, based on affinity chromatography, was compared with a previously (first generation) immunodepletion protocol using as a proof of principle the pan-African EchiTAb-Plus-ICP® IgG ...

        Second generation snake antivenomics: Comparing immunoaffinity and immunodepletion protocols 

        Pla Ferrer, Davinia; Gutiérrez, José María; Calvete Chornet, Juan José (2012-09-15)
        A second generation antivenomics protocol, based on affinity chromatography, was compared with a previously (first generation) immunodepletion protocol using as a proof of principle the pan-African EchiTAb-Plus-ICP® IgG ...

        Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches 

        Gutiérrez, José María; Sanz, Libia; Flores Díaz, Marietta; Figueroa, Lucía; Madrigal Villalobos, Marvin; Herrera Vega, María; Villalta Arrieta, Mauren; León Montero, Guillermo; Estrada Umaña, Ricardo; Borges, Adolfo; Alape Girón, Alberto; Calvete Chornet, Juan José (2010-10-21)
        Intraspecific snake venom variations have implications in the preparation of venom pools for the generation of antivenoms. The impact of such variation in the cross-reactivity of antivenoms against Bothrops asper venom was ...

        Pharmacokinetics of whole IgG equine antivenom: comparison between normal and envenomed rabbits 

        Quesada, Lil; Sevcik, Carlos; Lomonte, Bruno; Rojas Umaña, Ermila; Gutiérrez, José María (2006-09-01)
        Pharmacokinetics of antivenoms has been mainly studied in normal animals, whereas very little is known on pharmacokinetics in envenomed animals. The aim of this study was to compare pharmacokinetic parameters of whole IgG ...

        Pharmacokinetics of whole IgG equine antivenom: comparison between normal and envenomed rabbits 

        Quesada, Lil; Sevcik, Carlos; Lomonte, Bruno; Rojas Umaña, Ermila; Gutiérrez, José María (2006-09-01)
        Pharmacokinetics of antivenoms has been mainly studied in normal animals, whereas very little is known on pharmacokinetics in envenomed animals. The aim of this study was to compare pharmacokinetic parameters of whole IgG ...

        Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics 

        Gutiérrez, José María; Solano Trejos, María Gabriela; Pla Ferrer, Davinia; Herrera Vega, María; Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Vargas Arroyo, Mariángela; Sanz, Libia; Lomonte, Bruno; Calvete Chornet, Juan José; León Montero, Guillermo (2013-07)
        The assessment of the capacity of antivenoms to neutralize the lethal activity of snake venoms is the gold standard in the preclinical analysis of antivenom efficacy, and is routinely performed by manufacturers and quality ...

        Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics 

        Gutiérrez, José María; Solano Trejos, María Gabriela; Pla Ferrer, Davinia; Herrera Vega, María; Segura Ruiz, Álvaro; Villalta Arrieta, Mauren; Vargas Arroyo, Mariángela; Sanz, Libia; Lomonte, Bruno; Calvete Chornet, Juan José; León Montero, Guillermo (2013-07)
        The assessment of the capacity of antivenoms to neutralize the lethal activity of snake venoms is the gold standard in the preclinical analysis of antivenom efficacy, and is routinely performed by manufacturers and quality ...

        Intramuscular administration of antivenoms in experimental envenomation by Bothrops asper: comparison between Fab and IgG 

        Chaves Mora, Fernando; Loría Masís, Gilbert David; Salazar, Adriana; Gutiérrez, José María (2003-02)
        The efficacy of intramuscular (im) administration of sheep Fab and IgG antivenoms was assessed in a mouse experimental model of envenomation by Bothrops asper, in order to test if the more rapid absorption of Fab improves ...
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        Red de Repositorios Latinoamericanos
        + of 4.000.000
        Available publications
        163 Participating institutions
        Dirección de Servicios de Información y Bibliotecas (SISIB)
        Universidad de Chile
        Membership Login
        Featured collections
        • Latin American Theses
        • Argentinean Theses
        • Chilean Theses
        • Peruvian Theses
        Latest collections added
        • Argentina
        • Brazil
        • Colombia
        • México
        Dirección de Servicios de Información y Bibliotecas (SISIB)
        Universidad de Chile
        Red de Repositorios Latinoamericanos | 2006-2018