Now showing items 1-10 of 49
Metabolic syndrome and antipsychotics: The role of mitochondrial fission/fusion imbalance
(Frontiers Media SA, 2018)
Second-generation antipsychotics (SGAs) are known to increase cardiovascular risk through several physiological mechanisms, including insulin resistance, hepatic steatosis, hyperphagia, and accelerated weight gain. There ...
Efficacy and safety of atypical antipsychotic drugs (quetiapine, risperidone, aripiprazole and paliperidone) compared with placebo or typical antipsychotic drugs for treating refractory schizophrenia: overview of systematic reviews
(Associação Paulista de Medicina - APM, 2010-05-01)
CONTEXT AND OBJECTIVE: According to some cohort studies, the prevalence of refractory schizophrenia (RS) is 20-40%. Our aim was to evaluate the effectiveness and safety of aripiprazole, paliperidone, quetiapine and risperidone ...
Diabetes mellitus inducida por olanzapina: Caso clínico
(Sociedad Médica de Santiago, 2001)
Alteraciones metabólicas asociadas al uso de terapia antipsicótica
(Sociedad Médica de Santiago, 2009)
Esquizofrenia y su asociación con enfermedades médicas crónicas
(Sociedad Médica Santiago, 2017)
The life expectancy of patients with schizophrenia (SCH) is 11 to 20 years less than the general population. There is an association between SCH and various diseases and chronic conditions, highlighting the cardio-metabolic ...
A systematic review on clinical management of antipsychotic-induced sexual dysfunction in schizophrenia
(Associação Paulista de Medicina - APM, 2006-01-01)
INTRODUCTION: Sexual dysfunction frequently occurs in patients with schizophrenia under antipsychotic therapy, and the presence of sexual side effects may affect compliance. The aim of this study was to review and describe ...
Disruption of thalamocortical activity in schizophrenia models: relevance to antipsychotic drug action
(Cambridge University Press, 2013-11)
Non-competitive NMDA receptor antagonists are widely used as pharmacological models of schizophrenia due to their ability to evoke the symptoms of the illness. Likewise, serotonergic hallucinogens, acting on 5-HT2A receptors, ...