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Assessment of an anti-ageing structured cosmetic formulation containing goji berry
(2019-01-01)
Based on previous studies, it has been found that goji berry (GB), popularly known as a ‘miracle fruit’, has excellent antioxidant potential and can be used in the treatment of skin disorders associated with ageing. This ...
Pharmacokinetic and pharmacodynamic properties of carvedilol in fructose hypertensive rats
(Taylor & Francis, 2011-09)
The cardiovascular effects and mechanism of antihypertensive response of carvedilol were assessed in fructose fed rats using pharmacokinetic–pharmacodynamic (PK-PD) modelling. Male Sprague Dowley rats were randomly divided ...
Clinical pharmacology and therapeutic use of antioxidant vitamins
(2007)
The clinical use of antioxidants has gained considerable interest during the last decade. It was suggested from epidemiological studies that diets high in fruits and vegetables might help decrease the risk of cardiovascular ...
Ultrasound-assisted synthesis of novel chalcone, heterochalcone and bis-chalcone derivatives and the evaluation of their antioxidant properties and as acetylcholinesterase inhibitors
(Academic Press Inc., 2019)
The chalcone and bis-chalcone derivatives have been synthesized under sonication conditions via Claisen-Schmidt condensation with KOH in ethanol at room temperature (20–89%). The structures were established on the basis ...
Desenvolvimento e avaliação biofarmacêutica de supositórios de doxiciclina hiclato para uso veterinário
(Universidade Federal de Santa MariaBrasilAnálises Clínicas e ToxicológicasUFSMPrograma de Pós-Graduação em Ciências FarmacêuticasCentro de Ciências da Saúde, 2018-08-17)
Veterinary drug therapy can be quite laborious especially when performed in the home environment. Usually the animal drug treatment is done by the oral or injectable route, but the rectal route can be an alternative. The ...
Novel C-2 symmetric molecules as α-glucosidase and α-amylase inhibitors: Design, synthesis, kinetic evaluation, molecular docking and pharmacokinetics
(Molecular Diversity Preservation International, 2019-04)
A series of symmetrical salicylaldehyde-bishydrazine azo molecules, 5a?5h, have been synthesized, characterized by 1 H-NMR and 13 C-NMR, and evaluated for their in vitro α-glucosidase and α-amylase inhibitory activities. ...
Ultrasound-assisted synthesis of novel chalcone, heterochalcone and bis-chalcone derivatives and the evaluation of their antioxidant properties and as acetylcholinesterase inhibitors
(2019)
The chalcone and bis-chalcone derivatives have been synthesized under sonication conditions via Claisen-Schmidt condensation with KOH in ethanol at room temperature (20-89%). The structures were established on the basis ...
Changes in the activity of CYP450 3A4 induced by kaempferol 3-O-glucoside, major flavonol found in black bean (Phaseolus vulgaris) seed coat extract.
(2017-12-01)
Supplements have increase the popularity of herbal medicine as complementary and/or alternative therapies in the treatment of many disorders, because of this there is a potential possibility for pharmacokinetic and ...