Now showing items 1-10 of 674
Combinatorial synthesis and directed evolution applied to the production of alpha-helix forming antimicrobial peptides analogues
(Bentham Science Publ Ltd, 2006-12-01)
Antimicrobial peptides (AMPs) are effector molecules of innate immune systems found in different groups of organisms, including microorganisms, plants, insects, amphibians and humans. These peptides exhibit several structural ...
Study of the antimicrobial peptide indolicidin and a mutant in micelle medium by molecular dynamics simulation
The antimicrobial peptide indolicidin (IND) and the mutant CP10A in hydrated micelles were studied using molecular dynamics simulations in order to observe whether the molecular dynamics and experimental data could be ...
Synthesis and biophysics studies of threeantimicrobial peptides isolated from the scorpion pandinus imperator
Study of the antimicrobial peptide indolicidin and mutants in eukaryotic modelled membrane by molecular dynamics simulations
(TAYLOR & FRANCIS LTD, 2011)
In this work the interaction of the antimicrobial peptide indolicidin (IND) and its mutants CP10A and CP11 with a eukaryotic membrane model was examined by molecular dynamics simulations. The aim was to analyse the behaviour ...
Interaction of a synthetic antimicrobial peptide with model membrane by fluorescence spectroscopy
Static and time-resolved fluorescence of tryptophan and ortho-aminobenzoic acid was used to investigate the interaction of the synthetic antimicrobial peptide L1A (IDGLKAIWKKVADLLKNT-NH2) with POPC and POPC:POPG. N-acetylated ...
Monitoring the positioning of short polycationic peptides in model lipid bilayers by combining hydrogen/deuterium exchange and electrospray ionization mass spectrometry
(Elsevier B.V., 2008-12-01)
Electrospray ionization mass spectrometry (ESI-MS) was used to analyze the hydrogen/deuterium exchange properties of the mastoparan peptide Apoica-MP during interactions with lipid vesicle membranes. Synthetic peptide was ...
Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera)
(Elsevier B.V., 2004-06-01)
Four antimicrobial peptides were purified from Royal Jelly of honeybees, by using reverse phase-HPLC and sequenced by using Q-Tof-MS/MS: PFKLSLHL-NH2 (Jelleine-I), TPFKLSLHL-NH2 (Jelleine-II), EPFKLSLHL-NH2 (Jelleine-III), ...
Purification and characterization of an antimicrobial peptide produced by Pseudomonas sp strain 4B
An antimicrobial peptide produced by a bacterium isolated from the effluent pond of a bovine abattoir was purified and characterized. The strain was characterized by biochemical profiling and 16S rDNA sequencing as Pseudomonas ...
Study of the mechanism of action of anoplin, a helical antimicrobial decapeptide with ion channel-like activity, and the role of the amidated C-terminus
(John Wiley & Sons Ltd, 2008-06-01)
Anoplin, an antimicrobial, helical decapeptide from wasp venom, looses its biological activities by mere deamidation of its C-terminus. Secondary structure determination, by circular dichroism spectroscopy in amphipathic ...
Lipid-packing perturbation of model membranes by pH-responsive antimicrobial peptides
The indiscriminate use of conventional antibiotics is leading to an increase in the number of resistant bacterial strains, motivating the search for new compounds to overcome this challenging problem. Antimicrobial peptides, ...