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Caracterização química, atividades antioxidante, antileucêmica e antimicrobiana da própolis âmbar sul brasileira
(Universidade Federal do PampaCampus São Gabriel, 2017)
Structure-anti-leukemic activity relationship study of ortho- dihydroxycoumarins in U-937 cells: Key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action
(Pergamon-Elsevier Science Ltd, 2012-09)
Previous studies indicated the need of at least one phenolic hydroxyl group in the coumarin core for induction of cytotoxicity in different cell lines. Herein, we present an exhaustive structure-activity relationship study ...
SYNTHESIS OF DIBENZYLBUTANEDIOL LIGNANS AND THEIR ANTI-HIV, ANTI-HSV, ANTI-TUMOR ACTIVITIES
(Sociedad Chilena de Química, 2009)
Evaluation of the anti-proliferative effect the extracts of Allamanda blanchetti and A-schottii on the growth of leukemic and endothelial cells
(Canadian Soc Pharmaceutical SciencesEdmontonCanadá, 2006)
Xylodiol from Xylopia langsdorfiana induces apoptosis in HL60 cells
(Soc Brasileira FarmacognosiaJoao PessoaBrasil, 2011)
Linker for Activation of T-cell Family Member2 (LAT2) a Lipid Raft Adaptor Protein for AKT Signaling, Is an Early Mediator of Alkylphospholipid Anti-leukemic Activity
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INCBETHESDA, 2012)
Lipid rafts are highly ordered membrane domains rich in cholesterol and sphingolipids that provide a scaffold for signal transduction proteins; altered raft structure has also been implicated in cancer progression. We have ...
CFTR in K562 human leukemic cells
(American Physiological Society, 2003-08)
In this study, the expression and functional characterization of CFTR (cystic fibrosis transmembrane regulator) was determined in K562 chronic human leukemia cells. Expression of the CFTR gene product was determined by ...
CXCL12 is a costimulator for CD4+ T cell activation and proliferation in chronic lymphocytic leukemia patients
(Springer, 2013-01)
Activated T cells from patients with chronic lymphocytic leukemia (CLL) provide survival and proliferative signals to the leukemic clone within lymphoid tissues. Recruitment of both, CLL cells and T lymphocytes, to this ...