Now showing items 1-10 of 551
Determinants of anti-cancer effect of mitochondrial electron transport chain inhibitors: Bioenergetic profile and metabolic flexibility of cancer cells
(Bentham Science Publishers B.V., 2016)
© 2016 Bentham Science Publishers. Recent evidence highlights that energy requirements of cancer cells vary greatly from normal cells and they exhibit different metabolic phenotypes with variable participation of both ...
The need for effective radiosentitizing agents: experience in patients with complete pathological response
(LIPPINCOTT WILLIAMS & WILKINS, 2011)
Chemoradiation therapy is now considered the preferred initial treatment strategy for distal rectal cancer because of the observation of better local disease control and significant tumor downstaging. Downstaging has become ...
Neutropenia febril en el niño con cáncer: Conceptos actuales sobre criterios de riesgo y manejo selectivo
(Sociedad Médica de Santiago, 2001)
The pros and cons of targeting Protein Kinase C (PKC) in the management of cancer patients
(Bentham Science Publishers, 2011-11)
In the last years, PKC has become an attractive target for the treatment of cancer patients given its widely described role in carcinogenesis and tumor promotion. Despite the extensive research conducted on these phorbol ...
Brazilian natural dietary components (annatto, propolis and mushrooms) protecting against mutation and cancer
(Hodder Arnold, Hodder Headline Plc, 2006-05-01)
Considering the high number of new cancer cases in Brazil (approximately 470 000 cases in 2005) and the remarkable differences in the incidence of this disease around the world, the development of chemopreventive strategies ...
Synergistic interactions of the anti‑casein kinase 2 CIGB‑300 peptide and chemotherapeutic agents in lung and cervical preclinical cancer models
(Spandidos Publications, 2014-07)
CIGB‑300 is a novel clinical‑stage synthetic peptide that impairs the casein kinase 2 (CK2)‑mediated phosphorylation of B23/nucleophosmin in different experimental settings and cancer models. As a single agent, CIGB‑300 ...