Buscar
Mostrando ítems 1-10 de 589
Human repetitive and unique sequences coexist in a large circulating DNA species found in cryoprecipitates from SLE patients
(Clinical & Experimental Immunology, 2017)
Generation of sequence-specific, high affinity anti-DNA antibodies.
(American Society for Biochemistry and Molecular Biology, 2001-12)
By taking advantage of the extreme stability of a protein-DNA complex, we have obtained two highly specific monoclonal antibodies against a predetermined palindromic DNA sequence corresponding to the binding site of the ...
Staining of antinuclear antibodies and antibodies against removable nuclear antigens in connective tissue diseases
(Elsevier, 2020)
Introduction and objectives: Connective tissue diseases are inflammatory, autoimmune diseases and threaten quality of life. To determine the relationship between staining patterns of antinuclear antibodies and antibodies ...
Anti-C1q Antibodies in Juvenile-Onset Systemic Lupus Erythematosus
(BLACKWELL PUBLISHING, 2009)
The objective of this study was to evaluate the presence of anti-C1q antibodies Hospital Israelita Albert Einstein Research Institute, Sao Paulo, Brazil in 67 juvenile Systemic lupus erythematosus (JSLE) patients and 26 ...
Specific Recognition of a DNA Immunogen by its Elicited Antibody
(Academic Press Ltd - Elsevier Science Ltd, 2007-06)
DNA recognition by antibodies is a key feature of autoimmune diseases, yet model systems with structural information are very limited. The monoclonal antibody ED-10 recognizes one of the strands of the DNA duplex used in ...
Specific antibody-DNA interaction: a novel strategy for tight DNA recognition.
(American Chemical Society, 2003-12)
Anti-double-stranded DNA monoclonal antibodies against a viral transcriptional regulatory site are capable of discriminating single-base replacements with affinities of 1 x 10(-9) M, which were optimized for the length of ...
Autoimmunity, phospholipid-reacting antibodies and malaria immunity
(SAGE Publications, 2015)
Comparison of urinary parameters, biomarkers, and outcome of childhood systemic lupus erythematosus early onset-lupus nephritis
(2020-02-01)
Background: Urinary parameters, anti-dsDNA antibodies and complement tests were explored in patients with childhood-Systemic Lupus Erythematosus (cSLE) early-onset lupus nephritis (ELN) from a large multicenter cohort ...