Now showing items 1-10 of 412
Anti-nucleosome and anti-chromatin antibodies are present in active systemic lupus erythematosus but not in the cutaneous form of the disease
(SAGE PUBLICATIONS LTD, 2009)
The objective of this study is to investigate the presence of anti-nucleosome (anti-NCS) and anti-chromatin (anti-CRT) antibodies in patients with cutaneous lupus erythematosus (CLE) compared with active and inactive ...
Human repetitive and unique sequences coexist in a large circulating DNA species found in cryoprecipitates from SLE patients
(Clinical & Experimental Immunology, 2017)
Generation of sequence-specific, high affinity anti-DNA antibodies.
(American Society for Biochemistry and Molecular Biology, 2001-12)
By taking advantage of the extreme stability of a protein-DNA complex, we have obtained two highly specific monoclonal antibodies against a predetermined palindromic DNA sequence corresponding to the binding site of the ...
Anti-C1q Antibodies in Juvenile-Onset Systemic Lupus Erythematosus
(BLACKWELL PUBLISHING, 2009)
The objective of this study was to evaluate the presence of anti-C1q antibodies Hospital Israelita Albert Einstein Research Institute, Sao Paulo, Brazil in 67 juvenile Systemic lupus erythematosus (JSLE) patients and 26 ...
Specific Recognition of a DNA Immunogen by its Elicited Antibody
(Academic Press Ltd - Elsevier Science Ltd, 2007-06)
DNA recognition by antibodies is a key feature of autoimmune diseases, yet model systems with structural information are very limited. The monoclonal antibody ED-10 recognizes one of the strands of the DNA duplex used in ...
Specific antibody-DNA interaction: a novel strategy for tight DNA recognition.
(American Chemical Society, 2003-12)
Anti-double-stranded DNA monoclonal antibodies against a viral transcriptional regulatory site are capable of discriminating single-base replacements with affinities of 1 x 10(-9) M, which were optimized for the length of ...
Desenvolvimento de uma técnica imunoenzimática (ELISA) quantitativa para a pesquisa de anticorpos IgG anti-DNA nativo (DNAds) no lúpus eritematoso sistêmico Development of a quantitative enzyme-linked immunosorbent assay (ELISA) for the detection of anti-double-stranded (ds) DNA IgG antibodies in systemic lupus erythematosus
Isotipos IgG e IgM anti-dsDNA em pacientes com lúpus eritematoso sistêmico
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2012)
Anticorpos IgG anti-dsDNA se associam à ocorrência de nefrite lúpica. Relatos recentes sugerem que o isotipo IgM anti-dsDNA seja nefroprotetor. Avaliamos frequência de IgG anti-dsDNA em pacientes com lúpus eritematoso ...
Desempenho diagnóstico e associações clínicas dos anticorpos contra componentes da cromatina no lúpus eritematoso sistêmico juvenil
(Sociedade Brasileira de Reumatologia, 2012-10-01)
OBJECTIVES: To determine the frequency of antibodies to chromatin components in juvenile systemic lupus erythematosus (JSLE), and to correlate the presence of these autoantibodies with clinical manifestations and disease ...