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Ventricular Systolic Reserve in Asymptomatic Children Previously Treated With Low Doses of Anthracyclines
(2007-10-15)
Doppler echocardiography has been used for the diagnosis of anthracycline-induced cardiotoxicity. However, few data are available that include asymptomatic children previously treated with a low cumulative dose of this ...
Ventricular Systolic Reserve in Asymptomatic Children Previously Treated With Low Doses of Anthracyclines
(2007-10-15)
Doppler echocardiography has been used for the diagnosis of anthracycline-induced cardiotoxicity. However, few data are available that include asymptomatic children previously treated with a low cumulative dose of this ...
Characterisation of anthracyclines from a cosmomycin D-producing species of Streptomyces by collisionally-activated dissociation and ion mobility mass spectrometry
(IM PUBLICATIONS, 2009)
Cultures of cosmomycin D-producing Streptomyces olindensis ICB20 that were propagated for many generations underwent mutations that resulted in production of a range of related anthracyclines by the bacteria. The anthracyclines ...
DNA damage induced by the anthracycline cosmomycin D in DNA repair-deficient cells
(SPRINGER, 2010)
Anthracyclines have been widely used as antitumor agents, playing a crucial role in the successful treatment of many types of cancer, despite some side effects related to cardiotoxicity. New anthracyclines have been designed ...
MicroRNAs associated to anthracycline-induced cardiotoxicity in women with breast cancer: a systematic review and pathway analysis
(COL - SETOR DE PATOLOGIA CLINICAFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICASICB - DEPARTAMENTO DE GENÉTICA ECOLOGIA EVOLUÇÃO, 2020)
Background: Cardiotoxicity is a common and serious adverse effect of anthracycline therapy in breast cancer patients. The current criteria for cardiotoxicity are based on imaging and cardiac biomarkers. However, there is ...
Characterization Of The Changes In Cardiac Structure And Function In Mice Treated With Anthracyclines Using Serial Cardiac Magnetic Resonance Imaging
(Lippincott Williams & WilkinsPhiladelphia, 2016)