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Role of annexin 1 gene expression in mouse craniofacial bone development
(2007-07-01)
BACKGROUND: Annexin 1 is a 37-kDa protein that has complex intra- and extracellular effects. To discover whether the absence of this protein alters bone development, we monitored this event in the annexin-A1 null mice in ...
In vitro and in vivo studies on CCR10 regulation by Annexin A1
(Elsevier B.V., 2006-02-01)
The mode of action of annexin A1 (ANXA1) is poorly understood. By using rapid subtraction hybridization we studied the effects of human recombinant ANXA1 and the N-terminal ANXA1 peptide on gene expression in a human larynx ...
Annexin 1 mimetic peptide protects against renal ischemia/reperfusion injury in rats
(Springer, 2011-01-01)
Inflammation is currently recognized as a key mechanism in the pathogenesis of renal ischemia-reperfusion (I/R) injury. The importance of infiltrating neutrophil, lymphocytes, and macrophage in this kind of injury has been ...
Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis
(2006-04-01)
The recent appreciation of the role played by endogenous counterregulatory mechanisms in controlling the outcome of the host inflammatory response requires specific analysis of their spatial and temporal profiles. In this ...
Expression of annexin A1 mRNA in peripheral blood from oral squamous cell carcinoma patients
(Elsevier B.V., 2010-01-01)
Several studies have been suggesting annexin A1 protein as an active player in tumorigenesis of many organs. Nevertheless, its tumor biomarker role has been mainly studied in tissues by immunohistochemistry or cell culture. ...
Spatial expression of two anti-inflammatory mediators, annexin 1 and galectin-1, in nasal polyposis
(Blackwell Publishing, 2006-10-01)
Background There is renewed interest in the role played by specific counter-regulatory mechanisms to control the inflammatory host response, poorly investigated in human pathology. Here, we monitored the expression of two ...
Interaction of the Anti-Inflammatory Annexin A1 Protein and Tacrolimus Immunosuppressant in the Renal Function of Rats
(Karger, 2010-01-01)
Background: Tacrolimus (FK) is currently widely used in transplant immunosuppression and the treatment of autoimmune diseases. However, FK induces nephrotoxicity which is characterized by functional and structural renal ...
Effect of annexin-A1 peptide treatment during lung inflammation induced by lipopolysaccharide
(Academic Press Ltd Elsevier B.V. Ltd, 2012-08-01)
Lung endotoxemia is characterized by neutrophil accumulation, increased vascular permeability and parenchymal injury. This can also affect the endogenous pathways that operate in the host to keep inflammation under control. ...
Interaction of human neutrophils with endothelial cells regulates the expression of endogenous proteins annexin 1, galectin-1 and galectin-3
(Elsevier B.V., 2006-04-01)
Annexin 1 (ANXA1), galectin-1 (Gal-1) and galectin-3 (Gal-3) proteins have been identified as important mediators that promote or inhibit leukocyte migration. The expression of these proteins was studied in human neutrophils ...
Annexin 1: differential expression in tumor and mast cells in human larynx cancer
(Wiley-Blackwell, 2007-06-15)
Annexin 1 protein (ANXA1) expression was evaluated in tumor and mast cells in human larynx cancer and control epithelium. The effect of the exogenous ANXA1 (peptide Ac 2-26) was also examined during the cellular growth of ...