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Role of annexin 1 gene expression in mouse craniofacial bone development
(2007-07-01)
BACKGROUND: Annexin 1 is a 37-kDa protein that has complex intra- and extracellular effects. To discover whether the absence of this protein alters bone development, we monitored this event in the annexin-A1 null mice in ...
In vitro and in vivo studies on CCR10 regulation by Annexin A1
(Elsevier B.V., 2006-02-01)
The mode of action of annexin A1 (ANXA1) is poorly understood. By using rapid subtraction hybridization we studied the effects of human recombinant ANXA1 and the N-terminal ANXA1 peptide on gene expression in a human larynx ...
Spatial expression of two anti-inflammatory mediators, annexin 1 and galectin-1, in nasal polyposis
(Blackwell Publishing, 2006-10-01)
Background There is renewed interest in the role played by specific counter-regulatory mechanisms to control the inflammatory host response, poorly investigated in human pathology. Here, we monitored the expression of two ...
Annexin 1 mimetic peptide protects against renal ischemia/reperfusion injury in rats
(SPRINGER, 2011)
Inflammation is currently recognized as a key mechanism in the pathogenesis of renal ischemia-reperfusion (I/R) injury. The importance of infiltrating neutrophil, lymphocytes, and macrophage in this kind of injury has been ...
Formyl Peptide Receptors and Annexin A1: Complementary Mechanisms to Infliximab in Murine Experimental Colitis and Crohn’s Disease
(2021-09-17)
Non-responsiveness to anti-TNF-α therapies presents relevant rates in inflammatory bowel disease patients, presenting the need to find biomarkers involved in therapeutic efficacy. Herein, we demonstrate that higher levels ...
Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis
(2006-04-01)
The recent appreciation of the role played by endogenous counterregulatory mechanisms in controlling the outcome of the host inflammatory response requires specific analysis of their spatial and temporal profiles. In this ...
Annexin 6 modulates the maxi-chloride channel of the apical membrane of syncytiotrophoblast isolated from human placenta
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2004-11-26)
The syncytiotrophoblast separates the maternal and fetal blood and constitutes the primary barrier for maternal-fetal transport. The Maxi-chloride channel from the apical membrane of the syncytiotrophoblast plays a role ...
Expression of annexin A1 mRNA in peripheral blood from oral squamous cell carcinoma patients
(Elsevier B.V., 2010-01-01)
Several studies have been suggesting annexin A1 protein as an active player in tumorigenesis of many organs. Nevertheless, its tumor biomarker role has been mainly studied in tissues by immunohistochemistry or cell culture. ...
ANXA1 (annexin A1)
(2011)
The essential role of annexin A1 mimetic peptide in the skin allograft survival
(2013)
Immunosuppressive drugs have a critical role in inhibiting tissue damage and allograft rejection.Studies have demonstrated the anti-infl ammatory effects of the annexin A1 (AnxA1) in the regulationof transmigration and ...