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Increased Expression of Angiotensin II Type 2 Receptors in the Solitary-Vagal Complex Blunts Renovascular Hypertension
(Lippincott Williams & Wilkins, 2014-10-01)
Angiotensin II increases and decreases arterial pressure by acting at angiotensin type 1 and type 2 receptors, respectively. Renovascular hypertensive rats exhibit a high level of activity of the peripheral and central ...
Presence of angiotensin II and expression of angiotensin II type-2 receptor in human fallopian tube
(1998)
Objective: To determine the presence of angiotensin II and angiotensin II type-2 receptor subtype messenger RNA (mRNA) in human fallopian tube. Design: Frozen fallopian tubes were used for all studies. Setting: Procedures ...
Renin-angiotensin system as a potential target for new therapeutic approaches in Parkinson’s disease
(Taylor and Francis Ltd, 2017)
Renin-angiotensin system blockers and severe acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2, which is responsible for the current coronavirus
disease 2019 pandemic, uses angiotensin-converting enzyme 2 as a gateway into host cells. In this
review, we summarize the ...
Hypercholesterolemia modifies angiotensin II desensitisation and cross talk between α1-adrenoceptor and angiotensin AT1 receptor in rabbit aorta
(Elsevier Science, 2010-06)
This study characterised the effect of a hypercholesterolemic diet on the interactions of hormone receptors in the rabbit aorta, both in homologous desensitisation to angiotensin II and cross talk between α1-adrenoceptors ...
Evidence for changes in the tachyphylactic property of recombinant angiotensin II AT(1) receptor expressed in CHO cells
(Elsevier B.V., 2002-03-29)
The manifestation of tachyphylaxis to angiotensin 11 in Chinese hamster ovary (CHO) cells expressing the rat angiotensin II AT(1) receptor was investigated. the cells were transfected with a cDNA fragment containing the ...
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system
(2014)
Chronic RAS (renin-angiotensin system) activation by both AngII (angiotensin II) and aldosterone leads to hypertension and perpetuates a cascade of pro-hypertrophic, pro-inflammatory, pro-thrombotic and atherogenic effects ...
Effects of intracerebroventricular injections of losartan or PD123319 on arterial pressure and heart rate of sodium replete and sodium deplete rats
(1996-10-08)
Angiotensin II (Ang II) non-peptide antagonists were injected i.c.v. (6.25-200 nmol, n = 5-8 rats/group): In sodium replete rats, losartan (AT1 receptor antagonist) induced an increase in mean arterial pressure (MAP) and ...
Effects of intracerebroventricular injections of losartan or PD123319 on arterial pressure and heart rate of sodium replete and sodium deplete rats
(1996-10-08)
Angiotensin II (Ang II) non-peptide antagonists were injected i.c.v. (6.25-200 nmol, n = 5-8 rats/group): In sodium replete rats, losartan (AT1 receptor antagonist) induced an increase in mean arterial pressure (MAP) and ...