Throughout gestation, fetal membranes, also known as placental or amniochorion membranes, surround, and protect the fetus. Although a critical component of the intrauterine cavity, neither their cellular origin in embryo ...

A non-reversible state of epithelial to mesenchymal transition (EMT) at term accumulates proinflammatory mesenchymal cells and predisposes fetal membrane to weakening prior to delivery at term. We investigated the induction ...

To evaluate the mediators of the inflammatory response, in an in vitro model, of immortalized epithelial amniotic cells (hFM-AECs) challenged by different bacterial species, alone and in combinations with Mycoplasma hominis, ...

Oxidative stress (OS)-induced senescence of the amniochorion has been associated with parturition at term. We investigated whether telomere fragments shed into the amniotic fluid (AF) correlated with labor status and tested ...

Stem cells derived from placental tissues are an attractive source of cells for regenerative medicine. Amniotic epithelial cells isolated from human amnion (hAECs) have desirable and competitive characteristics that make ...

Dexamethasone (Dex), a corticosteroid hormone, is used during the perinatal period to help fetal lung and other organ development. Conversely, Dex-induced cell proliferation has been associated with accelerated aging. Using ...

Case report of a patient who developed failure of an allogenic living related conjunctival limbal transplantation in the right eye after an episode of epidemic keratoconjunctivitis. After a few months, she underwent ...

Introdução: O parto pré-termo espontâneo (PP) é considerado um dos principais problemas da clínica obstétrica e tem como uma das principais causas associada a infecção polibacteriana e consequente inflamação dos tecidos ...