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Thyroid dysfunction induced by amiodarone in clinical practiceDisfunción tiroidea inducida por amiodarona en la práctica clínica
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana, 2011)
Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure
(Academic Press Inc Elsevier Science, 2018-06)
Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side ...
Study of the influence of ascorbyl palmitate and amiodarone in the stability of unilamellar liposomes
(Taylor & Francis Ltd, 2014-03)
Amiodarone (AMI) is a low water-solubility drug, which is very useful in the treatment of severe cardiac disease. Its adverse effects are associated with toxicity in different tissues. Several antioxidants have been shown ...
Pharmacokinetic study of amiodarone in dogsEstudio farmacocinético de amiodarona en perros
(Archivos de Medicina Veterinaria, 1999)
Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole
(American Chemical Society, 2006-02)
There is no effective treatment for the prevalent chronic form of Chagas' disease in Latin America. Its causative agent, the protozoan parasite Trypanosoma cruzi, has an essential requirement for ergosterol, and ergosterol ...
Requirement for Ergosterol in V-ATPase Function Underlies Antifungal Activity of Azole Drugs
(Public Library of Science, 2010-06)
Ergosterol is an important constituent of fungal membranes. Azoles inhibit ergosterol biosynthesis, although the cellular basis for their antifungal activity is not understood. We used multiple approaches to demonstrate a ...
Cardiovascular drugs inducing QT prolongation: facts and evidence
(Bentham Science Publishers, 2010-01)
Acquired QT syndrome is mainly caused by the administration of drugs that prolong ventricular repolarization. On the other hand, the risk of drug-induced torsades de pointes is increased by numerous predisposing factors, ...
Reacciones adversas a fármacos : nivel de conocimiento
(Universidad Nacional de Cuyo. Facultad de Ciencias Médicas, 2018)