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Discovery and investigation of natural editing function against artificial amino acids in protein translation
(American Chemical Society, 2016-12)
Fluorine being not substantially present in the chemistry of living beings is an attractive element in tailoring novel chemical, biophysical, and pharmacokinetic properties of peptides and proteins. The hallmark of ...
Enhancement of polyunsaturated fatty acid production under low-temperature stress in Cylindrotheca closterium
(Springer, 2020-02-04)
Marine microalgae synthetize great amounts of essential metabolites such as fatty acids and amino acids. In addition, their exposure to stress factors can induce the overproduction of these desirable metabolites. Thus, in ...
Relationship between interannual variation of amino acid profile and pollen content in honey from a small Argentinian region
(American Chemical Society, 2006-12)
With the objective of evaluating the utility of the amino acid profile in the characterization of honey samples, 39 honey samples of two different harvests from a particular production zone in Córdoba, Argentina, were ...
Chiral x Achiral Multidimensional Liquid Chromatography. Application to the enantioseparation of dintitrophenyl amino acids in honey samples and their fingerprint classification
(Elsevier Science, 2019-11)
Most HPLC enantiomer separations are performed with columns packed with a chiral stationary phase (CSP) operated with an achiral mobile phase. The intrinsically limited chemical selectivity of most CSPs to the simultaneous ...
Physiological effects of glyphosate over amino acid profile in conventional and transgenic soybean (Glycine max)
(Academic Press Inc Elsevier Science, 2012-02)
This paper compares the responses of conventional and transgenic soybean to glyphosate application in terms of the contents of 17 detectable soluble amino acids in leaves, analyzed by HPLC and fluorescence detection. ...
Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents
(Elsevier, 2020-10)
Natural deep eutectic solvents (NADES) were introduced for the extraction of free seleno-amino acids from lyophilized and powdered milk samples. Different NADES were evaluated, and lactic acid:glucose (LGH) showed the ...
Reliable and simple analytical methods for determination of citrulline and metabolically related amino acids by liquid chromatography after derivatization: comparison between monolithic and core–shell columns
(Royal Society of Chemistry, 2014-08)
We describe the development of a high-performance liquid chromatography (HPLC) method for the determination of citrulline and other amino acids relevant to intestinal diseases. The amino acids were derivatized with ...
Optimisation of microwave-assisted acid hydrolysis for the determination of seleno-amino acids bound to proteins in powdered milk, lyophilized milk and infant formula
(Academic Press Inc Elsevier Science, 2019-06)
Selenium (Se) is an essential element present in milk as seleno-amino acids and seleno-proteins. To perform an accurate seleno-amino acid analysis, a complete hydrolysis of proteins is necessary. Microwave-assisted acid ...
Structural basis for the broad specificity of a new family of amino-acid racemases
(Wiley Blackwell Publishing, Inc, 2014-01)
Broad-spectrum amino-acid racemases (Bsrs) enable bacteria to generate noncanonical D-amino acids, the roles of which in microbial physiology, including the modulation of cell-wall structure and the dissolution of biofilms, ...
Comparative analysis reveals amino acids critical for anticancer activity of peptide CIGB-552
(John Wiley & Sons Ltd, 2016-11)
Because of resistance development by cancer cells against current anticancer drugs, there is a considerable interest in developing novel antitumor agents. We have previously demonstrated that CIGB-552, a novel cell-penetrating ...