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Expansion of CD4(+) CD25(+) Foxp3(+) T cells by bone marrow-derived dendritic cells
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Dendritic cells (DCs) are the most important antigen-presenting cells of the immune system and have a crucial role in T-lymphocyte activation and adaptive immunity initiation. However, DCs have also been implicated in ...
Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection
(Wiley-Blackwell, 2015)
CD4+CD25+Foxp3+ regulatory T (Treg) cells mediate immunological self-tolerance and
suppress immune responses. Retinoic acid (RA), a natural metabolite of vitamin A, has
been reported to enhance the differentiation of ...
Exogenous interleukin-33 targets myeloid-derived suppressor cells and generates periphery-induced Foxp3+ regulatory T cells in skin-transplanted mice
(Blackwell Publishing Ltd, 2015)
© 2015 John Wiley & Sons Ltd. Interleukin-33 (IL-33) has been a focus of study because of its variety of functions shaping CD4+ T-cell biology. In the present work, we evaluated the modulatory effect of IL-33 on suppressor ...
Allogeneic apoptotic thymocyte-stimulated dendritic cells expand functional regulatory T cells
(WILEY-BLACKWELL, 2011)
P>Dendritic cells (DCs) play an important role in the clearance of apoptotic cells. The removal of apoptotic cells leads to peripheral tolerance, although their role is still not clear. We show that the uptake of apoptotic ...
Retinoic acid generates regulatory T cells in experimental transplantation
(2011)
Regulatory T cells play a key role to inhibit effector lymphocytes, avoid, autoimmunity, and restrain allogeneic immunity. Retinoic acid is an important cofactor that stimulates the generation and expansion of regulatory ...
Exogenous interleukin-33 targets myeloid-derived suppressor cells and generates periphery-induced Foxp3(+) regulatory T cells in skin-transplanted mice
(Wiley-Blackwell, 2015)
Interleukin-33 (IL-33) has been a focus of study because of its variety of
functions shaping CD4+ T-cell biology. In the present work, we evaluated
the modulatory effect of IL-33 on suppressor cells in an in vivo ...
Dendritic Cells and B Cells Cooperate in the Generation of CD4+CD25+FOXP3+ Allogeneic T Cells
(2010)
Background: CD4+CD25+Foxp3+ regulatory T cells (Treg) play an essential role in immune tolerance, suppressing responses against self-antigens. Additionally, Treg play an important role in maintaining immunosuppression to ...
Patients with oral squamous cell carcinoma are characterized by increased frequency of suppressive regulatory T cells in the blood and tumor microenvironment
(SPRINGER, 2010)
Oral squamous cell carcinoma (OSCC) is a cancerous lesion with high incidence worldwide. The immunoregulatory events leading to OSCC persistence remain to be elucidated. Our hypothesis is that regulatory T cells (Tregs) ...
Immune Regulatory Properties of Allogeneic Adipose-Derived Mesenchymal Stem Cells in the Treatment of Experimental Autoimmune Diabetes
(AMER DIABETES ASSOCALEXANDRIA, 2012)
Adipose-derived mesenchymal stem cells (ADMSCs) display immunosuppressive properties, suggesting a promising therapeutic application in several autoimmune diseases, but their role in type 1 diabetes (T1D) remains largely ...