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Current advances in targeted therapies for metastatic gastric cancer: improving patient care
(Future medicine ltd, 2016)
In this article, we review the literature on the current advances in targeted therapies for metastatic gastric cancer aimed at improving patient care. We conclude that the key to guiding targeted therapy is individual ...
Long non-coding RNAs in gastric cancer: mechanisms and potential applications.
(2016)
Gastric cancer is the third leading cause of cancer mortality worldwide. Unfortunately, most gastric cancer cases are diagnosed in an advanced, non-curable stage with a limited response to chemotherapy. Recent findings in ...
Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer
(Associação Brasileira de Divulgação Científica, 2008)
Gastric cancer is the forth most frequent malignancy and the second most common cause of cancer death worldwide. DNA methylation is the most studied epigenetic alteration, occurring through a methyl radical addition to the ...
Mevalonate pathway as a novel target for the treatment of metastatic gastric cancer
(2020-10)
Gastric mucosa tumors may present as two distinct major entities: Diffuse and intestinal subtypes. There is no
standard treatment for advanced or metastatic gastric cancer. The mevalonate pathway and cholesterol homeostasis ...
Role of Reprimo-like as a a tumor suppressor and candidate biomarker in gastric cancer
(2020)
Reprimo-like (RPRML) is an uncharacterized member of the Reprimo gene family. Herein, we evaluated the role of RPRML and whether its regulation by DNA methylation is a potential non-invasive biomarker of gastric cancer. ...
Immunology of Human Gastric Cancer: A Preliminary Report
(the American Cancer Society, lnc., 2017)
Emerging role of miRNas in the drug resistance of gastric cancer
(2016)
Gastric cancer is the third leading cause of cancer mortality worldwide. Unfortunately, most gastric cancer cases are diagnosed in an advanced, non-curable stage and with a limited response to chemotherapy. Drug resistance ...
Gastric cancer: Nanoparticles as tools to improve treatment efficacy
(Bentham Science, 2016)
In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths ...