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Localization of adhesins on the surface of a pathogenic bacterial envelope through atomic force microscopy
(Royal Society of Chemistry, 2015-11)
Bacterial adhesion is the first and a significant step in establishing infection. This adhesion normally occurs in the presence of flow of fluids. Therefore, bacterial adhesins must be able to provide high strength ...
Adhesins of Brucella: Their Roles in the Interaction with the Host
(Molecular Diversity Preservation International, 2020-11)
A central aspect of Brucella pathogenicity is its ability to invade, survive, and replicate in diverse phagocytic and non-phagocytic cell types, leading to chronic infections and chronic inflammatory phenomena. Adhesion ...
Salicylic acid enhances Staphylococcus aureus extracellular adhesin protein expression
(Elsevier Science, 2011-11)
One of the virulence factors required by Staphylococcus aureus at the early stages of infection is Eap, a secreted adhesin that binds many host proteins and is upregulated by the two-component regulatory system saeRS. The ...
A genomic island in Brucella involved in the adhesion to host cells: identification of a new adhesin and a translocation factor
(Wiley Blackwell Publishing, Inc, 2020-07)
Adhesion to host cells is the first step in the virulence cycle of any pathogen. In Gram-negative bacteria, adhesion is mediated, among other virulence factors such as the lipopolysaccharides, by specific outer-membrane ...
The BtaF Adhesin Is Necessary for Full Virulence During Respiratory Infection by Brucella suis and Is a Novel Immunogen for Nasal Vaccination Against Brucella Infection
(Frontiers Media S.A., 2019-07-26)
Brucella enters their hosts mostly through mucosae from where it spreads systemically.Adhesion to extracellular matrix (ECM) components or to host cells is important for theinfectious process, and is mediated by several ...
Distribution of saa gene variants in verocytotoxigenic Escherichia coli isolated from cattle and food
(Elsevier Science, 2006-04)
The pathogenesis of verocytotoxigenic Escherichia coli (VTEC) infection in humans is multifactorial, given that verocytotoxins are the principal virulence factor. Most strains causing serious diseases possess the eae gene ...
Staphylococcus aureus isolates from chronic osteomyelitis are characterized by high host cell invasion and intracellular adaptation, but still induce inflammation
(Elsevier Gmbh, 2014-11)
Osteomyelitis is a severe inflammatory disease of the bone that is mainly caused by Staphylococcus aureus. Particularly, bone infections are difficult to treat and can develop into a chronic course with a high relapsing ...