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Heteroleptic tris-chelate ruthenium(II) complexes of N,N-disubstituted-N '-acylthioureas: Synthesis, structural studies, cytotoxic activity and confocal microscopy studies
(Elsevier B.V., 2017-04-18)
Ruthenium complexes have been assessed as anti-tumor agents against cancer cells. In this project, new heteroleptic rutheniuM(II) complexes with general formulae [Ru(L)(bipy)(dppb)](PF6) (where L = N,N-disubstituted-N'-a ...
Structure/activity of PtII/N,N-Disubstituted-N’-acylthiourea complexes: Anti-tumor and anti-mycobacterium tuberculosis activities
(2018-06-01)
The syntheses, characterization, cytotoxicity against tumor cells and anti-Mycobacterium tuberculosis activity assays of PtII/PPh3/N,N-disubstituted-N’-acylthioureas complexes with general formulae [Pt(PPh3)2(L)]PF6, PPh3 ...
Synthesis, characterization, and crystal structure of Ni(II) and Cu(II) complexes with N-furoyl-N',N'-diethylthiourea: antifungal activity
(Taylor and FrancisColchester, 2011-08)
The complexes cis-bis(N-furoyl-N′,N′-diethylthioureato-k 2O,S)nickel(II) and cis-bis(N-furoyl-N′,N′-diethylthioureato-k 2O,S)copper(II) were prepared by the reaction of metal acetate with the corresponding acylthiourea ...
INTERACTION OF N-ACYLTHIOUREA NICKEL(II) CHELATES WITH NITROGEN BASES IN SOLUTION AND IN THE SOLID-STATE
(Elsevier Science Sa LausanneLausanne 1Suíça, 1984)
Propriedades citotóxicas de complexos de Cu(I)-Trifenilfosfina com ligantes aciltioureias ou naftoquinonas
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2021-07-26)
In this work, the synthesis, characterization, and evaluation of the cytotoxic activity of sixteen Cu(I)/Triphenylphosphine complexes containing the acylthiourea or naphthoquinones ligands are presented. The complexes were ...
The trans-[Ru(PPh3)(2)(N,N-dimethyl-N '-thiophenylthioureato-k(2)O,S)(bipy)] PF6 complex has pro-apoptotic effects on triple negative breast cancer cells and presents low toxicity in vivo
(Elsevier B.V., 2018-09-01)
Triple negative breast cancer (TNBC) is a heterogeneous subtype of breast tumors that does not exhibit the expression of estrogen and progesterone receptors, neither the amplification of the human epidermal growth factor ...
Vibrational spectra and molecular structure of isomeric 1-(adamantan-1-ylcarbonyl)-3-(dichlorophenyl)thioureas
(Elsevier Science, 2017-02)
1-(adamantan-1-ylcarbonyl)-3-(2,3-dichlorophenyl)thiourea, 1, and 1-(adamantan-1-ylcarbonyl)-3-(2,5-dichlorophenyl)thiourea, 2, were synthesized in reasonable yields from admanantyl-1-carbonyl chloride and ammonium thiocyanate ...
Supramolecular self-assembly of a coumarine-based acylthiourea synthon directed by π-stacking interactions: Crystal structure and Hirshfeld surface analysis
(Elsevier Science, 2016-05)
The structure of 1-(2-oxo-2H-chromene-3-carbonyl)-3-(2-methoxy-phenyl)thiourea (1) has been determined by single-crystal X-ray crystallography. This compound crystallizes in the monoclinic space group P21/c with a = 7.455 ...
Palladium(II)/N,N-disubstituted-N′-acylthioureas complexes as anti-Mycobacterium tuberculosis and anti-Trypanosoma cruzi agents
(2017-01-01)
The new complexes of Pd(II) with N,N-disubstituted-N′-acylthioureas:[(1) [Pd(dppf)(N,N-dimethyl-N′-benzoylthioureato-k2O,S)]PF6, (2) [Pd(dppf)(N,N-diethyl-N′-benzoylthioureato-k2O,S)]PF6, (3) [Pd(dppf)(N,N-dibuthyl-N′-be ...
Estudo de complexos metálicos de RuII, NiII, PdII e PtII com ligantes aciltioureias: atividade citotóxica e interação com biomoléculas
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2019-12-20)
In this work, two series of phosphine complexes containing acylthiourea ligands were synthesized, characterizatied and evaluatied of the cytotoxic activities. The first series of compounds was composed of complexes with ...