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Comparative time-course study of aminoacyl- and dipeptidyl-resin hydrolysis
(1997-12-01)
The classic hydrolysis procedure for quantification of resin-bound aminoacyl and peptidyl groups with 12 N HCl: propionic acid was recvaluated by studying the influence of the nature of the resin and the resin-bound group. ...
Comparative time-course study of aminoacyl- and dipeptidyl-resin hydrolysis
(1997-12-01)
The classic hydrolysis procedure for quantification of resin-bound aminoacyl and peptidyl groups with 12 N HCl: propionic acid was recvaluated by studying the influence of the nature of the resin and the resin-bound group. ...
Analogues of Human Granulysin as Antimycobacterial Agents
(Springer, 2019-06)
Antimicrobial peptides are essential components of innate defense mechanisms and make promising candidates for novel anti-infective agents. The advantages of these peptides in clinical applications include their potential ...
On the role of surrounding regions in the fusion peptide in dengue virus infection
(2021-05-01)
Dengue virus infection depends on its fusion with the host membrane, where the binding occurs through interaction between proteins on the virus cell surface and specific viral receptors on target membranes. This process ...
Des-Acyl Ghrelin Directly Targets the Arcuate Nucleus in a Ghrelin- Receptor Independent Manner and Impairs the Orexigenic Effect of Ghrelin
(Wiley Blackwell Publishing, Inc, 2016-02)
Ghrelin is a stomach-derived octanoylated peptide hormone that plays a variety of well-established biological roles acting via its specific receptor known as growth hormone secretagogue receptor (GHSR). In plasma, a ...
Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties
(Wiley Blackwell Publishing, Inc, 2011-07)
A series of peptide analogs based on region 6-22 of Plantaricin 149 sequence were synthesized. The interaction between these analogs and phospholipid-polydiacetylene vesicles was investigated to evaluate the ability of the ...
Circulating ghrelin concentrations are lowered by intracerebroventricular insulin
(SpringerNew YorkEUA, 2006)
Ca(2+)-mediated thiolysis of peptide-resin linkage as an option for preparing protected peptide thioesters
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
A mild new procedure for preparing protected peptide thioesters, based oil Ca(2+)-assisted thiolysis of peptide-Kaiser oxime resin (KOR) linkage, is described. Ac-Ile-Ser(Bzl)-Asp(OcHx)-SR (Ac: acetyl; Bzl: benzyl; cHx: ...
Plasma levels of ghrelin, des-acyl ghrelin and LEAP2 in children with obesity: Correlation with age and insulin resistance
(BioScientifica, 2019-11)
Objective: The octanoylated peptide hormone ghrelin regulates appetite and glycaemic control. Des-acyl ghrelin abolishes some effects of ghrelin, but does not bind to ghrelin receptor. LEAP2 is a novel ligand for ghrelin ...