Now showing items 1-10 of 70
Molecular basis for the diagnosis and treatment of acute promyelocytic leukemia
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2012)
Acute promyelocytic leukemia is characterized by gene rearrangements that always involve the retinoic acid receptor alpha on chromosome 15. In the majority of patients t(15;17) is detected, which generates the promyelocytic ...
Noninvasive Ventilation in a Pregnant Patient With Respiratory Failure From All-Trans-Retinoic-Acid (ATRA) Syndrome
(Daedalus Enterprises IncIrvingEUA, 2009)
Acute leukemias in Piaui: comparison with features observed in other regions of Brazil
(Assoc Bras Divulg CientificaSao PauloBrasil, 2003)
Coagulation abnormalities in acute promyelocytic leukemia
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2009)
Acute promyelocytic leukemia is frequently accompanied by coagulation abnormalities usually described as laboratorial disseminated intravascular coagulation, which is the main cause of morbidity and early mortality. Aberrant ...
The CEBPA gene is down-regulated in acute promyelocytic leukemia and its upstream promoter, but not the core promoter, is highly methylated
(FERRATA STORTI FOUNDATION, 2011)
impairment of CCAAT Enhancer Binding Protein alpha (CEBPA) function is a common finding in acute myeloid leukemia; nevertheless, its relevance for acute promyelocytic leukemia pathogenesis is unclear. We analyzed the ...
Role of Microparticles in the Hemostatic Dysfunction in Acute Promyelocytic Leukemia
(THIEME MEDICAL PUBL INC, 2010)
Serious bleeding and thrombotic complications are frequent in acute promyelocytic leukemia (APL) and are major causes of morbidity and mortality. Microparticles (MP) have been used to study the risk and pathogenesis of ...
Acute promyelocytic leukemia associated with the PLZF-RARA fusion gene: two additional cases with clinical and laboratorial peculiar presentations
(HUMANA PRESS INCTOTOWA, 2012)
Acute promyelocytic leukemia (APL) is characterized by the presence of the t(15;17) and PML-RARa rearrangement, with good response to treatment with retinoids. However, few cases of variant APL involving alternative ...
Guidelines On The Diagnosis And Treatment For Acute Promyelocytic Leukemia: Associação Brasileira De Hematologia, Hemoterapia E Terapia Celular Guidelines Project: Associação Médica Brasileira - 2013
(Sociedade Brasileira de Hematologia e Hemoterapia, 2014)
Differentiation syndrome in acute promyelocytic leukemia: pathogenesis and risk factors
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2008)
Differentiation syndrome is a treatment complication which can occur in acute promyelocytic leukemia (APL) patients treated with all-trans retinoic acid (ATRA) or arsenic trioxide (ATO), which is characterized by enhanced ...