Buscar
Mostrando ítems 1-10 de 40
A role for the small GTPase Rac1 in vaccinia actin-based motility
(Taylor & Francis, 2014-10-31)
Vaccinia virus dissemination relies on the recruitment of the nucleation promoting factor N-WASP underneath cell-associated extracellular virus (CEVs) and subsequent recruitment and activation of the ARP2/3 complex, a major ...
The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility
(Rockefeller Univ Press, 2013-09-23)
Vaccinia virus dissemination relies on the N-WASP– ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs). Here, we uncover a previously unappreciated role for the formin ...
The metalloprotease Mpl supports Listeria monocytogenes dissemination through resolution of membrane protrusions into vacuoles
(American Society for Microbiology, 2016-06)
Listeria monocytogenes is an intracellular pathogen that disseminates within the intestinal epithelium through acquisition of actin-based motility and formation of plasma membrane protrusions that project into adjacent ...
Caracterização de Actina 4 de Trypanosoma cruzi
(Fundação Oswaldo Cruz. Instituto Carlos Chagas., 2019)
Motility, morphology and phylogeny of the plasmodial worm, Ceratomyxa vermiformis n. sp (Cnidaria: Myxozoa: Myxosporea)
(Cambridge Univ Press, 2017)
The Myxozoa demonstrate extensive morphological simplification and miniaturization relative to their free-living cnidarian ancestors. This is particularly pronounced in the highly derived myxosporeans, which develop as ...
p38γ promotes breast cancer cell motility and metastasis through regulation of RhoC GTPase, cytoskeletal architecture, and a novel leading edge behavior
(American Association for Cancer Research, 2011-10)
Understanding the molecular alterations that confer cancer cells with motile, metastatic properties is needed to improve patient survival. Here, we report that p38γ motogen-activated protein kinase regulates breast cancer ...
O envolvimento da proteína cinase PAK1 na infecção pelo Orthopoxvirus vaccinia: implicações para a disseminação viral
(Universidade Federal de Minas GeraisUFMG, 2012-03-06)
An efficient virus multiplication cycle results from a complex network of virus-host interactions culminating with a propitious intracellular environment for the generation and spread of virus progeny. Interfering with ...
Regulation of Dendritic Cell Migration by CD74, the MHC Class II-Associated Invariant Chain
(AMER ASSOC ADVANCEMENT SCIENCE, 2008-12-12)
Dendritic cells ( DCs) sample peripheral tissues of the body in search of antigens to present to T cells. This requires two processes, antigen processing and cell motility, originally thought to occur independently. We ...
Estudio de la Miosina C de Plasmodium falciparum (PfMYO-C)
(Maestría en Ciencias Básicas BiomédicasUniversidad El BosqueFacultad de Medicina, 2011)
De las cinco especies de Plasmodium que causan la malaria, P. falciparum es la que produce la mayor mortalidad en el mundo, a pesar de los esfuerzos de los países endémicos por implementar diferentes estrategias para su ...
Apparent stiffness of vimentin intermediate filaments in living cells and its relation with other cytoskeletal polymers
(Elsevier Science, 2020-08)
The cytoskeleton is a complex network of interconnected biopolymers intimately involved in the generation and transmission of forces. Several mechanical properties of microtubules and actin filaments have been extensively ...