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Functional expression of the α7 and α4-containing nicotinic acetylcholine receptors on the neonatal rat carotid body
(2012)
The carotid bodies (CBs) are chemosensory organs that respond to hypoxemia with transmitter neurosecretion, leading to a respiratory reflex response. It has been proposed that acetylcholine is a key regulator of transmitter ...
Molecular modeling of the α9α10 nicotinic acetylcholine receptor subtype
(2009)
This study reports the comparative molecular modeling, docking and dynamic simulations of human α9α10 nicotinic acetylcholine receptors complexed with acetylcholine, nicotine and α-conotoxin RgIA, using as templates the ...
Acetylcholine contributes to control the physiological inflammatory response during the peri-implantation period
(Wiley Blackwell Publishing, Inc, 2015-06)
Maternal antigen-presenting cells attracted to the pregnant uterus interact with trophoblast cells and modulate their functional profile to favour immunosuppressant responses. Non-neuronal cholinergic system is expressed ...
Molecular modeling of the a9a10 nicotinic acetylcholine receptor subtype
(Elsevier Ltd., 2008-10-25)
This study reports the comparative molecular modeling, docking and dynamic simulations of human
a9a10 nicotinic acetylcholine receptors complexed with acetylcholine, nicotine and a-conotoxin RgIA,
using as templates the ...
Supplementing female rats with DHA-lysophosphatidylcholine increases docosahexaenoic acid and acetylcholine contents in the brain and improves the memory and learning capabilities of the pups
(2010-03)
DHA has been established. We propose that DHAcontaining
lysophosphatidylcholine (DHA-LPC), obtained
from DHA-rich eggs may be a suitable form of DHA and
choline (the precursor of acetylcholine) supplementation.
We ...
Functional characterization of acetylcholine receptors and calcium signaling in rat testicular capsule contraction
(Elsevier B.V., 2013-08-15)
The motor activity of mammalian testicular capsule (TC) contributes to male fertility and infertility, but the acetylcholine receptors related to the contractions induced by cholinergic drugs are poorly known. Indeed to ...
Electrogravimetric Analysis by Quartz-Crystal Microbalance on the Consumption of the Neurotransmitter Acetylcholine by Acetylcholinesterase
(2012-12-01)
Electrogravimetric analysis was performed on the consumption of the neurotransmitter Acetylcholine (ACh) by Acetylcholinesterase (AChE) in situ and in real time. Michaelis-Menten assumption was achieved by using an enzyme ...
Electrogravimetric Analysis by Quartz-Crystal Microbalance on the Consumption of the Neurotransmitter Acetylcholine by Acetylcholinesterase
(2012-12-01)
Electrogravimetric analysis was performed on the consumption of the neurotransmitter Acetylcholine (ACh) by Acetylcholinesterase (AChE) in situ and in real time. Michaelis-Menten assumption was achieved by using an enzyme ...
The alpha 7, alpha 4 beta 2 and alpha 3 beta 4 Nicotinic Acetylcholine Receptors: Characteristics, Role in Pathogenic Processes and Bioactive Compounds
(Brazilian Chemical Soc, 2016-01-01)
Neuronal nicotinic acetylcholine receptors (nAChRs) are potential targets for the treatement of several central nervous system disorders, including Alzheimer's disease, Parkinson's disease and schzophrenia. On this review ...