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Neural, cellular and molecular mechanisms of active forgetting
(Frontiers Media SA, 2018-02)
The neurobiology of memory formation attracts much attention in the last five decades. Conversely, the rules that govern and the mechanisms underlying forgetting are less understood. In addition to retroactive interference, ...
Soluble tumor necrosis factor alpha promotes retinal ganglion cell death in glaucoma via calcium-permeable ampa receptor activation
(Society for Neuroscience, 2015-09)
Loss of vision in glaucoma results from the selective death of retinal ganglion cells (RGCs). Tumor necrosis factorα (TNFα) signaling has been linked to RGC damage, however, the mechanism by which TNFα promotes neuronal ...
Functional reduction of SK3-mediated currents precedes AMPA-receptor-mediated excitotoxicity in dopaminergic neurons
(Pergamon-Elsevier Science Ltd, 2011-06)
In primary cultures of mesencephalon small-conductance calcium-activated potassium channels (SK) are expressed in dopaminergic neurons. We characterized SK-mediated currents (ISK) in this system and evaluated their role ...
Cross-sensitization between cocaine and acute restraint stress is associated with sensitized dopamine but not glutamate release in the nucleus accumbens
(Wiley Blackwell Publishing, Inc, 2013-03)
Repeated administration of psychostimulant drugs or stress can elicit a sensitized response to the stimulating and reinforcing properties of the drug. Here we explore the mechanisms in the nucleus accumbens (NAc) whereby ...
Emotional stress induces structural plasticity in Bergmann glial cells via an AC5–CPEB3–GluA1 pathway
(Society for Neuroscience, 2020-04)
Stress alters brain function by modifying the structure and function of neurons and astrocytes. The fine processes of astrocytes are critical for the clearance of neurotransmitters during synaptic transmission. Thus, ...
Glyphosate and atrazine in rainfall and soils in agroproductive areas of the pampas region in Argentina
(Elsevier Inc, 2018-12)
The presence in the atmosphere of glyphosate (GLP) and atrazine (ATZ) was investigated—those pesticides dominating the market in Argentina—through rain, as the main climatic phenomenon associated with wet deposition, both ...
Effect of ionotropic and metabotropic glutamate agonists and D-aspartate on prolactin release from anterior pituitary cells
(Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2002-03)
Although the presence of ionotropic (iGluRs) and metabotropic (mGluRs) glutamate receptors has been demonstrated in the anterior pituitary, recent reports on the direct effect of glutamate on prolactin (PRL) secretion by ...
Methamphetamine blunts Ca2+ currents and excitatory synaptic transmission through D1/5 receptor-mediated mechanisms in the mouse medial prefrontal cortex
(Wiley Blackwell Publishing, Inc, 2016-05)
Psychostimulant addiction is associated with dysfunctions in frontal cortex. Previous data demonstrated that repeated exposure to methamphetamine (METH) can alter prefrontal cortex (PFC)-dependent functions. Here, we show ...
Differental effects of glatamate agonist and D-aspartate on oxytocin release from hypothalamus and posterior pituitary of male rats.
(Humana Press, 2001-12)
In order to determine whether ionotropic (iGluRs) and metabotropic (mGluRs) glutamate receptor activation modulates oxytocin release in male rats, we investigated the effect of agonists of both types of glutamate receptors ...