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Alginate Lyase and Ciprofloxacin Co-Immobilization on Biopolymeric Microspheres for Cystic Fibrosis Treatment
(Wiley, 2013-08-21)
A new formulation is described based on biopolymeric microspheres containing alginate lyase (AL) and ciprofloxacin (Cip) for sustainable oral delivery in CF patients. Alginate (ALG) and high-methoxyl pectin (HMP) are ...
Characterization of smart auto-degradative hydrogel matrix containing alginate lyase to enhance levofloxacin delivery against bacterial biofilms
(Elsevier Science, 2015-12)
The aim of the present work is the characterization of smart auto-degradable microspheres composed of calcium alginate/high methoxylated pectin containing an alginate lyase (AL) from Sphingobacterium multivorum and ...
The role of alginate lyases in the enzymatic saccharification of brown macroalgae, Macrocystis pyrifera and Saccharina latissima
(Elsevier, 2017)
In this work, we have compared the carbohydrate content and the enzymatic saccharification of the brown algae Macrocystis pyrifera from Chile and Saccharina latissima from Norway. M. pyrifera contained 40% mannitol, 31% ...
Development of novel alginate lyase cross-linked aggregates for the oral treatment of cystic fibrosis
(Royal Society of Chemistry, 2014)
Alginate lyase (AL) from Sphingobacterium multivorum is unsuitable for oral delivery because of its rapid inactivation under acidic conditions. The synthesis of a novel crosslinking enzyme aggregate (CLEA) of AL (AL-CLEA) ...
Development and characterization of new enzymatic modified hybrid calcium carbonate microparticles to obtain nano-architectured surfaces for enhanced drug loading
(Elsevier Inc, 2015-02)
Hypothesis: Biopolymer–CaCO3 hybrid microparticles exposed to hydrolytic enzymes can provide new surface tailorable architectures. Soluble Alginate Lyase hydrolyzed alginate chains exposed on microparticle surface are ...
Isolation and characterization of an Antarctic Flavobacterium strain with agarase and alginate lyase activities
(CIENCIAS, 2016)
Several bacteria that are associated with macroalgae can use phycocolloids as a carbon source. Strain INACH002, isolated from decomposing Porphyra (Rhodophyta), in King George Island, Antarctica, was screened and characterized ...
Comparison of different types of pretreatment and enzymatic saccharification of Macrocystis pyrifera for the production of biofuel
(Elsevier, 2016)
In this work, the brown algae Macrocystis pyrifera were pretreated with dilute sulfuric acid, water and three different types of ionic liquids (ILs): 1-ethyl-3-methylimidazolium acetate ([EMIM][OAc]), 1,5-diazabicyclo[4.3.0] ...