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The interaction of RAAS inhibitors with COVID-19: Current progress, perspective and future
Coronavirus disease 2019 (COVID -19), caused by severe acute respiratory syndrome coronavirus 2 (SARS -CoV-2), is currently defined as the worst pandemic disease. SARS -CoV-2 infects human cells via the binding of its ...
Comprehensive Evaluation of the Effects of Enalapril on Matrix Metalloproteinases Levels in Hypertension
ACE as a Mechanosensor to Shear Stress Influences the Control of Its Own Regulation via Phosphorylation of Cytoplasmic Ser(1270)
(PUBLIC LIBRARY SCIENCE, 2011)
Objectives: We tested whether angiotensin converting enzyme (ACE) and phosphorylation of Ser(1270) are involved in shear-stress (SS)-induced downregulation of the enzyme. Methods and Results: Western blotting analysis ...
ACE gene polymorphism and severe lung injury in patients with COVID-19
COVID-19 has markedly varied clinical presentations, with the majority of patients being asymptomatic or having mild symptoms. However, severe acute respiratory disease caused by SARS-CoV-2 is common and associated with ...
Perindopril regulates β-agonist-induced cardiac apoptosis
Administration of the β-adrenergic agonist isoproterenol results in cardiac apoptosis, The effect of short-term β-adrenergic stimulation by isoproterenol on the activity of plasma, lung, and left ventricular (LV) angiotensin ...