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One-electron reduction of 6-hydroxydopamine quinone is essential in 6-hydroxydopamine neurotoxicity
(2013)
6-Hydroxydamine has widely been used as neurotoxin in preclinical studies related on the neurodegenerative process of dopaminergic neurons in Parkinson's disease based on its ability to be neurotoxic as a consequence of ...
The c-Abl/p73 pathway induces neurodegeneration in a Parkinson's disease model
(2022)
Parkinson's disease is the second most common neurodegenerative disorder. Although it is clear that dopaminergic neurons degenerate, the underlying molecular mechanisms are still unknown, and thus, successful treatment is ...
Time course of deficits in open field behavior after unilateral neostriatal 6-hydroxydopamine lesions
(2002)
In this study, the degree and time course of deficits in open field behavior was analyzed in male Wistar rats (aged 1 year) which had received unilateral neostriatal lesions with 6-OHDA. The post-mortem neurochemical ...
Time course of deficits in open field behavior after unilateral neostriatal 6-hydroxydopamine lesions
(2002)
In this study, the degree and time course of deficits in open field behavior was analyzed in male Wistar rats (aged 1 year) which had received unilateral neostriatal lesions with 6-OHDA. The post-mortem neurochemical ...
Lesion of the bulbospinal noradrenergic pathways blocks desipramine-induced inhibition of the C-fiber evoked nociceptive reflex in rats
(2001)
Desipramine-induced inhibition of spinal cord nociceptive transmission was studied in rats with or without lesion of the bulbospinal noradrenergic system by recording the C-fiber evoked nociceptive reflex from a hind limb. ...
Rapid increase of nurr1 expression in the substantia nigra after 6-hydroxydopamine lesion in the striatum of the rat
(JOHN WILEY & SONS LTDA., 2003)