Now showing items 1-10 of 665
Di erences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5-HT2A and 5-HT2C receptors
(Nature Publishing Group, 2002-04-04)
1 The pharmacological pro®le of a series of (+)-2,5-dimethoxy-4-(X)-phenylisopropylamines (X=I, Br, NO2, CH3, or H) and corresponding phenylethylamines, was determined in Xenopus laevis oocytes injected with cRNA coding ...
5-HT2 and 5-HT3 receptors in the lateral parabrachial nucleus mediate opposite effects on sodium intake
(Elsevier B.V., 2007-06-08)
The present study investigated the role of several 5-HT receptor subtypes in the lateral parabrachial nucleus (LPBN) in the control of sodium appetite (i.e. NaCl consumption). Male Holtzman rats had cannulas implanted ...
Characterization of the feeding behavior induced by agonists 5-HT1A, 5-HT1B, 5-HT2A and 5-HT2CCaracterización de la conducta alimentaria inducida por agonista s 5-ht1a, 5-ht1b, 5-ht2a y 5-ht2c
(Sociedad Mexicana de Análisis de la Conducta / Mexican Society of Behavior Analysis, 2009)
5-HT(1A/1B), 5-HT(6), and 5-HT(7) serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: Role of dorsal raphe nucleus
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009)
Pharmacological studies have been focused on the involvement of different neural pathways in the organization of antinociception that follows tonic-clonic seizures, including 5-hydroxytryptamine (5-HT)-, norepinephrine-, ...
Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons
(John Wiley and Sons Inc., 2014)
Serotonin (5-HT) production and expression of 5-HT receptors (5-HTRs) occur early during prenatal development. Recent evidence suggests that, in addition to its classical role as a neurotransmitter, 5-HT regulates neuronal ...
4-Bromo-2,5-dimethoxyphenethylamine (2C-B) and structurally related phenylethylamines are potent 5-HT 2A receptor antagonists in Xenopus laevis oocytes
1 We recently described that several 2-(2,5-dimethoxy-4-substituted phenyl)ethylamines (PEAs), including 4-I = 2C-I, 4-Br = 2C-B, and 4-CH 3 = 2C-D analogs, are partial agonists at 5-HT 2C receptors, and show low or even ...
Activation of 5-HT2C (but not 5-HT1A) receptors in the amygdala enhances fear-induced antinociception: Blockade with local 5-HT2C antagonist or systemic fluoxetine
It is well-known that the exposure of rodents to threatening environments [e.g., the open arm of the elevated-plus maze (EPM)] elicits pain inhibition. Systemic and/or intracerebral [e.g., periaqueductal gray matter, ...