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Prognostic significance of α‐ and β2‐adrenoceptor gene expression in breast cancer patients
(The British Pharmacological Society, 2019-07)
Breast cancer is the most frequently diagnosed and leading cause of cancer death among women worldwide. It was classified within molecular intrinsic subtypes: luminal A, luminal B, human epidermal growth factor receptor ...
Measurement of inverse agonism in β-adrenoceptors
(Elsevier Inc, 2010-12)
Increasing numbers of compounds, previously classified as antagonists, were shown to inhibit this spontaneous or constitutive receptor activity, instead of leave it unaffected as expected for a formal antagonist. In addition, ...
Activation of β 3 adrenergic receptor decreases DNA synthesis in human skin fibroblasts via cyclic GMP/nitric oxide pathway
(Karger, 2005-07)
Background: Evidences have shown that β 1 and β 2 adrenoceptors co-exist in human fibroblasts, but it is not yet clear the functional expression of β 3 adrenoceptor in these cells. The aim of this study was to investigate ...
Different b-adrenoceptor subtypes coupling to cAMP or NO/cGMP pathways : implications in the relaxant response of rat conductance and resistance vessels
(WileyGrupo de Investigación de Tecnología en Regencia de FarmaciaLondres, Inglaterra, 2022)