Now showing items 1-10 of 519
General Concepts of Skeletal Muscle and Apoptosis: Molecular Mechanisms and Regulation by Sex Steroids
(Bentham Science Publishers, 2019)
Apoptosis is a physiologic process that take place during development andin the progression of specific diseases. In skeletal muscle, this process is poorly explored. Skeletal muscle represents an exceptional tissue regards ...
Role of androgen receptor in the protective action of testosterone during apoptosis in skeletal muscle
(Elsevier Science Inc, 2011-12)
Expression and subcellular distribution of native estrogen receptor β in murine C2C12 cells and skeletal muscle tissue
(Elsevier Science Inc, 2009-06)
We have recently described the expression and intracellular localization of ER α in murine C2C12 cells and skeletal muscle tissue. In separate studies, a protective role of 17β-estradiol against apoptosis exerted mainly ...
17β-Estradiol signaling in skeletal muscle cells and its relationship to apoptosis
(Elsevier Science Inc, 2008-10)
17β-Estradiol exerts an antiapoptotic action in skeletal muscle cells through extranuclear ERα and β. This protective action, mainly involves a non-genomic mechanism of ERK1/2 and PI3K/Akt activation and BAD phosphorylation. ...
The antiapoptotic effect of 17ß-estradiol in skeletal muscle cells involves PKCδ, JNK and p66Shc
(Elsevier Science Inc, 2016-02)
The hormone 17β-Estradiol (E2) acts on several non-reproductive tissues,including skeletal muscle. We have shown that E2 at physiological concentrations prevented apoptosis induced by hydrogen peroxide (H2O2) in skeletal ...
Troponin T3 regulates nuclear localization of the calcium channel Cavβ1a subunit in skeletal muscle
(Elsevier Inc, 2015-08)
The voltage-gated calcium channel (Cav) β1a subunit (Cavβ1a) plays an important role in excitation-contraction coupling (ECC), a process in the myoplasm that leads to muscle-force generation. Recently, we discovered that ...
Expression and localization of estrogen receptor α in the C2C12 murine skeletal muscle cell line
(Wiley-liss, Div John Wiley & Sons Inc, 2008-07)
The classical model of 17β-estradiol action has been traditionally described to be mediated by the estrogen receptor (ER) localized exclusively in the nucleus. However, there is increasing functional evidence for extra ...