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AC biosusceptometry and magnetic nanoparticles to assess doxorubicin-induced kidney injury in rats
(Future Medicine Ltd, 2020-02-01)
Aim: This paper aims to investigate a doxorubicin (DOX) chronic kidney disease rat model using magnetic nanoparticles (MNPs) associated with the alternate current biosusceptometry (ACB) to analyze its different perfusion ...
Bothrops alternatus Snake Venom Induces Cytokine Expression and Oxidative Stress on Renal Function
(Bentham Science Publ Ltd, 2019-01-01)
Background: Envenomation caused by Bothrops alternatus is common in Southern Brazil. Acute Kidney Injury occurs after Bothrops snakebite and more information is necessaryrequired to understand its mechanism. Objective: The ...
Bothrops pauloensis snake venom-derived Asp-49 and Lys-49 phospholipases A2 mediates acute kidney injury by oxidative stress and release of inflammatory cytokines
(2021-01-30)
The envenomation caused by the Bothrops pauloensis snake leads to severe local and systemic effects including acute kidney injury. In this study, we investigated the renal effects by phospholipases A2 (PLA2s), divided into ...
Phosphodiesterase-5 inhibitor sildenafil attenuates kidney injury induced by Bothrops alternatus snake venom
(2021-10-30)
Acute kidney injury pathogenesis in envenoming by snakes is multifactorial and involves immunologic reactions, hemodynamic disturbances, and direct nephrotoxicity. Sildenafil (SFC), a phosphodiesterase 5 inhibitor, has ...
Renal effects of Bunodosoma caissarum crude extract: Prostaglandin and endothelin involvement
(2017-11-01)
Sea anemones contain a variety of interesting biologically active compounds, including some potent toxins. PLA2 from Bunodosoma caissarum, a sea anemone endemic in the Brazilian southern coast, has shown renal alterations ...
Bothrops leucurus venom induces nephrotoxicity in the isolated perfused kidney and cultured renal tubular epithelia
(2013-01-01)
Bites from snake (Bothrops genus) cause local tissue damage and systemic complications, which include alterations such as hemostatic system and acute renal failure (ARF). Recent studies suggest that ARF pathogenesis in ...
Renal toxicity of Bothrops moojeni snake venom and its main myotoxins
(Pergamon-elsevier Science LtdOxfordInglaterra, 2002)
Renal effects and vascular reactivity induced by Tityus serrulatus venom
(Elsevier B.V., 2005-09-01)
Tityus serrulatus, popularly known as yellow scorpion, is one of the most studied scorpion species in South America and its venom has supplied some highly active molecules. The effects of T. serrulatus venom upon the renal ...
Perspectiva veterinaria del sistema renal en la sepsis
(2021-01-01)
This paper aims to review, discuss and define the factors associated with development of kidney injury in patients with sepsis, diagnosis alternatives, therapy and prevention, offering to the veterinarians an updated guide ...
Renal and vascular effects of Crotalus durissus cumanensis venom and its crotoxin fraction
(Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP), 2011-01-01)
In this study, we evaluated the actions of Crotalus durissus cumanensis venom (CDCmV), and its crotoxin (Crtx) fraction, on renal and vascular functions in Wistar rats. In isolated perfused kidneys, CDCmV (10 mu g/mL) ...