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New primers for the amplification and sequencing of nuclear loci in a taxonomically wide set of reptiles and amphibians
(Springer, 2010-09-01)
We report new primers for the amplification and sequencing of 11 nuclear markers in squamate reptiles and anuran amphibians (five in squamates, six in anurans). Ten out of the 11 loci are introns (three of which are linked) ...
Identification of protein-coding and intronic noncoding RNAs down-regulated in clear cell renal carcinoma
(Wiley-Blackwell, 2008-10-01)
The clear cell subtype of renal cell carcinoma (RCC) is the most lethal and prevalent cancer of the urinary system. To investigate the molecular changes associated with malignant transformation in clear cell RCC, the gene ...
COX24 codes for a mitochondrial protein required for processing of the COX1 transcript
(2006-02-10)
In most strains of Saccharomyces cerevisiae the mitochondrial gene COX1, for subunit 1 of cytochrome oxidase, contains multiple exons and introns. Processing of COX1 primary transcript requires accessory proteins factors, ...
Identification and characterization of polymorphisms within the 5' flanking region, first exon and part of first intron of bovine GH gene
(Blackwell Publishing, 2006-06-01)
The aim of the present study was to identify and characterize polymorphisms within the 5' flanking region, first exon and part of first intron of the bovine growth hormone gene among different beef cattle breeds: Nelore ...
β-casein gene polymorphism permits identification of bovine milk mixed with bubaline milk in mozzarella cheese
(2008-12-01)
Mozzarella cheese is traditionally prepared from bubaline (Bubalus bubalis) milk, but product adulteration occurs mainly by addition of or full substitution by bovine milk. The aim of this study was to show the usefulnes ...
Influence of eNOS gene polymorphism on cardiometabolic parameters in response to physical training in postmenopausal women
(Associação Brasileira de Divulgação Científica (ABRADIC), 2011-09-01)
The health-promoting effects of exercise training (ET) are related to nitric oxide (NO) production and/or its bioavailability. The objective of this study was to determine whether single nucleotide polymorphism of the ...
Interferon-gamma+874 Polymorphism in the First Intron of the Human Interferon-gamma Gene and Kidney Allograft Outcome
(Elsevier B.V., 2010-12-01)
Background. Despite advances in immunosuppressive therapy in the past decade, allograft rejection remains an important cause of kidney graft failure. Cytokines play a major role in the inflammatory and immune responses ...
Prevalência de dislipidemia em adultos de meia-idade com polimorfismo do gene NOS3 e baixa aptidão cardiorrespiratória
(Sociedade Brasileira de Endocrinologia e Metabologia, 2013-02-01)
OBJETIVO: Analisar a influência da associação dos polimorfismos do gene da sintase do óxido nítrico endotelial (NOS3) para as posições -786T>C, Glu298Asp e íntron 4b/a e a aptidão cardiorrespiratória sobre as concentrações ...
Analysis of Factor VIII polymorphic markers as a means for carrier detection in Brazilian families with haemophilia A
(Blackwell Publishing, 2007-07-01)
Haemophilia A is an X-linked, recessively inherited bleeding disorder of varying severity, which results from the deficiency of procoagulant factor VIII f(8). Linkage diagnosis using polymorphic markers in the f8 gene is ...
Estrogen receptor alpha polymorphism and susceptibility to uterine leiomyoma
(Elsevier B.V., 2006-11-01)
Uterine leiomyoma is the most frequent pelvic tumor found in female genital tract. Some studies have suggested an association between single nucleotide polymorphisms (SNPs) in estrogen receptors genes with susceptibility ...