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The importance of drug repurposing in the field of antiepileptic drug development
(Springer, 2016)
Drug repurposing involves finding new therapeutic uses for existing drugs, including marketed, discontinued, shelved, and investigational drugs. The advantages of this strategy are many: reduced drug development timeline, ...
Drug Binding to Plasma Proteins
(Springer Nature Switzerland AG, 2021)
After absorption, most drugs will distribute heterogeneouslyacross tissues and organs, with the total drug concentration in plasmagenerally not being representative of the total concentration in other tissues.The main ...
Rational Pharmacotherapy in Infectious Diseases: Issues Related to Drug Residues in Edible Animal Tissues
(Multidisciplinary Digital Publishing Institute, 2021-10)
Drugs are used in veterinary medicine to prevent or treat animal diseases. When rationally administered to livestock following Good Veterinary Practices (GVP), they greatly contribute to improving the production of food ...
Potential Pharmacokinetic Drug-Drug Interactions between Cannabinoids and Drugs Used for Chronic Pain
(Hindawi Publishing Corporation, 2020-08)
Choosing an appropriate treatment for chronic pain remains problematic, and despite the available medication for its treatment, still, many patients complain about pain and appeal to the use of cannabis derivatives for ...
Two-dimensional transport analysis of transdermal drug absorption with a non-perfect sink boundary condition at the skin-capillary interface
(ELSEVIER SCIENCE INC, 2013-07-01)
A transient percutaneous drug absorption model was solved in two dimensions. Clearance of the topically-applied pharmaceutical occured at the skin-capillary boundary. Timolol penetration profiles in the dermal tissue were ...
Anthelmintic therapy in ruminant species: Understanding of the host-drug-parasite interaction
(Bentham Science Publishers, 2010-05)
Inadequate use of anthelmitic drugs in livestock animals has led to therapeutic failures and to the dramatic widespread development of parasite resistance. Additional scientific knowledge on how to improve the use of ...
Enzyme Induction and Drug Metabolism
(Springer Nature Switzerland AG, 2021)
Enzyme induction is one of the most important underlying mechanism of drug-drug interactions (DDIs). It can be defined as an increase in the biosynthesis of metabolizing enzymes after the exposure of the organism to ...
Drug interaction in GeriatricsInteracción medicamentosa en Geriatría
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana, 2004)
Anticestodal and antitrematodal drugs
(Wiley Blackwell Publishing, Inc, 2009)
ANTICESTODAL DRUGS Introduction Bunamidine Niclosamide Praziquantel Epsiprantel ANTITREMATODAL DRUGS Introduction. Fasciolosis. Nitrophenolic compounds: nitroxynil, disophenol, niclofolan Salicylanilides: closantel, ...