Now showing items 1-10 of 138
Doxycycline hyclate: a review of properties, applications and analytical methods
The doxycycline hyclate is a broad-spectrum antibiotic oxytetracycline synthetic derivative used in several countries. It has been used to treat infectious diseases and as an additive in animal nutrition to facilitate ...
A simple spectrophotometry method for the determination of tetracycline and doxycycline in pharmaceutical formulations using chloramine-T
A simple, rapid, accurate and inexpensive spectrophotometric method for the determination of tetracycline and doxycycline has been developed. The method is based on the reaction between these drugs and chloramine-T in ...
Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways
In neurodegenerative diseases, the inflammatory response is mediated by activated glial cells, mainly microglia, which are the resident immune cells of the central nervous system. Activated microglial cells release ...
Therapy with adjunctive doxycycline local delivery in patients with type 1 diabetes mellitus and periodontitis
(Blackwell MunksgaardCopenhagenDinamarca, 2004)
Characterization Of The Release Profile Of Doxycycline By Plga Microspheres Adjunct To Non-surgical Periodontal Therapy
(TAYLOR & FRANCIS LTDABINGDON, 2015)
Assessment of metalloproteinase inhibitors clodronate and doxycycline in the neutralization of hemorrhage and coagulopathy induced by Bothrops asper snake venom
Snake venom metalloproteinases (SVMPs) play a prominent role in the local and systemic manifestations of viperid snakebite envenomations. Thus, the possibility of using metalloproteinase inhibitors in the treatment of these ...
Quantification of Doxycycline Hyclate in Tablets by HPLC-UV Method
(Oxford University Press, 2013-11-01)
An accurate, sensitive, precise and rapid gradient reversed-phase high-performance liquid chromatographic method was successfully developed and validated for the determination of doxycycline hyclate in bulk drug and tablets. ...
Increasing Doxycycline Hyclate Photostability by Complexation with beta-Cyclodextrin
Doxycycline hyclate (DOX) is a highly photosensitive drug, a feature that limits the stability of the corresponding dosage forms. The main objectives of this work were the preparation and characterization of an inclusion ...