Now showing items 1-10 of 127
Trypanosoma cruzi 175-kDa protein tyrosine phosphorylation is associated with host cell invasion
(Academic Press Inc, 1998-06-01)
We examined the requirement of Trypanosoma cruzi protein tyrosine phosphorylation for parasite entry into mammalian cells and analyzed the profile of phosphorylated proteins in infective trypomastigotes. Treatment of ...
QSAR analysis of nicotinamidic compounds and design of potential Bruton’s tyrosine kinase (Btk) inhibitors
(Taylor and Francis Online, 2018)
Tyrosine phosphorylation is increased in the rat hippocampus during the status epilepticus induced by pilocarpine
(Elsevier B.V., 1998-09-01)
Phosphorylation of tyrosine residue in proteins is an important modulatory process for membrane transduction and cell signaling and for several cellular functions. the concentration and distribution of phosphotyrosine ...
Nitric oxide and cGMP activate the Ras-MAP kinase pathway-stimulating protein tyrosine phosphorylation in rabbit aortic endothelial cells
(Elsevier B.V., 2003-08-15)
The free radical nitric oxide is a very effective signal transducer, stimulating the enzyme guanylyl cyclase, the oncoprotein p21Ras, and protein tyrosine phosphorylation. in the present study using rabbit aortic endothelial ...
Biochemical characterization of a protein tyrosine phosphatase from Trypanosoma cruzi involved in metacyclogenesis and cell invasion
(Elsevier B.V., 2011-05-13)
Protein tyrosine phosphatases (PTPs) form a large family of enzymes involved in the regulation of numerous cellular functions in eukaryotes. Several protein tyrosine phosphatases have been recently identified in trypanosomatides. ...
Epithelial cells treated with genistein inhibit adhesion and endocytosis of Paracoccidioides brasiliensis
Paracoccidioidomycosis is caused by Paracoccidioides brasiliensis, which although not formally considered an intracellular pathogen, can be internalized by epithelial cells in vitro and in vivo. The mechanisms used by P. ...
Schistosonia mansoni: Expression of Fes-like tyrosine kinase SmFes in the tegument and terebratorium suggests its involvement in host penetration
(Elsevier B.V., 2007-07-01)
Protein Tyrosine Kinases (PTKs) are important molecules in intra- and inter-cellular communication, playing a major role in signal transduction processes. We have previously identified and characterized the molecular ...
Purification and characterization of the active form of tyrosine hydroxylase from mesangial cells in culture
The capacity of mesangial cells (MC) to produce catecholamines (CAs) has been investigated in our laboratory. To study the CA cascade, it is necessary to examine some steps in their metabolic pathway. Tyrosine hydroxylase ...
Cocaine-induced behavioral sensitization in adolescent rats endures until adulthood: Lack of association with GluR1 and NR1 glutamate receptor subunits and tyrosine hydroxylase
(Pergamon-Elsevier B.V. Ltd, 2008-11-01)
Exposure to repeated cocaine induces enduring behavioral sensitization, which has been implicated in the psychostimulant-induced craving and psychosis. Adaptations in dopamine and glutamate neurotransmission in the nucleus ...
Lack of association between bipolar disorder and tyrosine hydroxylase: A meta-analysis
Tyrosine hydroxylase (TH) is a candidate gene extensively explored in several association studies of bipolar disorder (BD). However, because of conflicting results of independent studies and low statistical power of ...