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Association of calcium density in the thoracic aorta with risk factors and clinical events
(Springer, 2020-02)
Objectives: In the ascending aorta, calcification density was independently and inversely associated with cardiovascular disease (CVD) risk prediction. Until now, the density of thoracic aorta calcium (TAC) was estimated ...
Comprehensive assessment of local and regional aortic stiffness in patients with tricuspid or bicuspid aortic valve aortopathy using magnetic resonance imaging
(Elsevier Ireland, 2020-11)
Background: We aimed to provide a comprehensive aortic stiffness description using magnetic resonance imaging (MRI) in patients with ascending thoracic aorta aneurysm and tricuspid (TAV-ATAA) or bicuspid (BAV) aortic valve. ...
Effects of carvedilol or amlodipine on target organ damage in L-NAME hypertensive rats: their relationship with blood pressure variability
(Elsevier, 2017-04)
The aim of the study was to compare the effects of chronic oral treatment with carvedilol or amlodipine on blood pressure, blood pressure variability and target organ damage in N-nitro-l-arginine methyl ester (L-NAME) ...
MicroRNA dysregulation in pulmonary arteries from chronic obstructive pulmonary disease: Relationships with vascular remodeling
(American Thoracic Society, 2018-10)
Pulmonary vascular remodeling is an angiogenic-related process involving changes in smooth muscle cell (SMC) homeostasis, which is frequently observed in chronic obstructive pulmonary disease (COPD). MicroRNAs (miRNAs) are ...
Canonical transient receptor potential 6 channel deficiency promotes smooth muscle cells dedifferentiation and increased proliferation after arterial injury
(Elsevier, 2020-07)
Objective Previous studies showed the benefit of canonical transient receptor potential 6 (TRPC6) channel deficiency in promoting endothelial healing of arterial injuries in hypercholesterolemic animals. Long-term studies ...
Lipoproteína “a”: elevaciones extremas y polimorfismos genéticos, asociación con lesiones cardíacas y vasculares evaluadas por tomografíaLipoprotein a: Extreme Elevation and Genetic Polymorphism Association with Cardiac and Vascular Lesions Evaluated by Computed Tomography
(Sociedad Argentina de Cardiología, 2017-05)
Introducción: La lipoproteína a [Lp(a)] es una partícula compleja, similar a una lipoproteína de baja densidad, asociada con una molécula de apolipoproteína “a” [apo(a)]. La concentración elevada de Lp(a) plasmática se ...
Effects of chronic carvedilol administration on blood pressure variability and target organ injury in rats with sinoaortic denervationEfectos de la administración crónica de carvedilol sobre la variabilidad de la presión arterial y el daño de órgano blanco en ratas con desnervación sinoaórtica
(Sociedad Argentina de Cardiología, 2015-06)
Background: Increased blood pressure variability is a novel risk factor for the development of target organ injury both in hypertensive and normotensive subjects, so its reduction should be considered as a new therapeutic ...
High fat diet-induced metabolically obese and normal weight rabbit model shows early vascular dysfunction: mechanisms involved
(Nature Publishing Group, 2018-09)
Background: Obesity contributes significantly to the development and evolution of cardiovascular disease (CVD) which is believed to be mediated by oxidative stress, inflammation and endothelial dysfunction. However, the ...
Prognostic Value of Vascular Calcifications and Regional Fat Depots Derived From Conventional Chest Computed Tomography
(Lippincott Williams, 2019-01)
Purpose: The prognostic value of vascular calcifications as well as of regional fat depots has been reported separately, in population-based studies, and using gated-computed tomography (CT) examinations. We, therefore, ...