Now showing items 1-10 of 147
Encapsulação da rifampicina em matrizes poliméricas flutuantes obtidas por liofilização a partir de metilcelulose e ftalato de hidroxipropilmetilcelulose. Avaliação da liberação in vitro
Floating multiparticles for oral administration with different compositions were studied from a matricial polymeric system to obtain sustained release. The polymers used in the multiparticles constitution were methylceullose ...
LC Evaluation of In Vitro Release of AZT from Microemulsions
A reversed phase LC method was developed and validated to analyze the in vitro release of AZT from microemulsions. A mobile phase of acetonitrile:water (15:85) was used. The method validation showed good selectivity and ...
Novel sustained-release of stryphnodendron obovatum leaves extract using natural rubber latex as carrier
Natural rubber latex biomembranes (NRL), obtained from rubber tree Hevea brasiliensis (Willd. ex A. Juss.) Mull. Arg., have been used as sustained drug release of drugs and plant extracts with medicinal properties. The ...
Modeling a system of phosphated cross-linked high amylose for controlled drug release. Part 2: Physical parameters, cross-linking degrees and drug delivery relationships
(Elsevier B.V., 2009-04-17)
High amylose cross-linked to different degrees with sodium trimetaphosphate by varying base strength (2% or 4%) and contact time (0.5-4 h) was evaluated as non-compacted systems for sodium diclophenac controlled release. ...
Development and in vitro evaluation of lyotropic liquid crystals for the controlled release of dexamethasone
In this study, amphiphilic polymers were investigated as biomaterials that can control dexamethasone (DXM) release. Such materials present interfacial properties in the presence of water and an oily phase that can result ...
Release properties of chemical and enzymatic crosslinked gelatin-gum Arabic microparticles containing a fluorescent probe plus vetiver essential oil
(Elsevier Science BvAmsterdamHolanda, 2008)
Physicochemical aspects involved in methotrexate release kinetics from biodegradable spray-dried chitosan microparticles
(Elsevier B.V., 2015-06-01)
Spray dried methotrexate (MTX) loaded chitosan microparticles were prepared using different drug/copolymer ratios (9%, 18%, 27% and 45% w/w). The physicochemical aspects were assessed in order to select particles that were ...
Electrospraying technique for the fabrication of metronidazole contained PLGA particles and their release profile
(Elsevier Science, 2015-11)
Advanced engineering of materials for the development of drug delivery devices provides scope for novel and versatile strategies for treatment of various diseases. 'Electrospraying' was used to prepare PLGA microparticles ...
Polyacrylic acid polymers hydrogels intended to topical drug delivery: preparation and characterization
(Informa Healthcare, 2015-06-01)
Context: Bioadhesiviness of polyacrylic acid polymers make them promising hydrogels to design topical drug delivery systems, allowing a close contact with biological substrate as well as an enhanced local concentration ...