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Crosstalk between Rac1- mediated actin regulation and ROS production
(Elsevier, 2018)
The small RhoGTPase Rac1 is implicated in a variety of events related to actin cytoskeleton rearrangement. Remarkably, another event that is completely different from those related to actin regulation has the same relevance; ...
Inclusion complexes of chloramphenicol with β-cyclodextrin and aminoacids as a way to increase drug solubility and modulate ROS production
(Elsevier, 2015-05)
The aim of this study was to improve the solubility of chloramphenicol and reduce the production of reactive oxygen species (ROS) in leucocytes induced by this drug, using complexation. Multicomponent complexes were prepared ...
Osteoblast Adhesion Dynamics: A Possible Role for ROS and LMW-PTP
(Wiley-Blackwell, 2014-06-01)
Reactive oxygen species (ROS) modulate a variety of intracellular events, but their role in osteoblast adhesion and spreading remains unclear. ROS is a very-known physiological modulators of Protein Tyrosine Phosphatases ...
Molecular link between auxin and ROS-mediated polar growth
(National Academy of Sciences, 2017-05)
Root hair polar growth is endogenously controlled by auxin and sustained by oscillating levels of reactive oxygen species (ROS). These cells extend several hundred-fold their original size toward signals important for plant ...
Molecular link between auxin and ROS-mediated polar growth
(National Academy of Sciences, 2017-05)
Root hair polar growth is endogenously controlled by auxin and sustained by oscillating levels of reactive oxygen species (ROS). These cells extend several hundred-fold their original size toward signals important for plant ...
oiwa, a Female Gametophytic Mutant Impaired in a Mitochondrial Manganese-Superoxide Dismutase, Reveals Crucial Roles for Reactive Oxygen Species during Embryo Sac Development and Fertilization in Arabidopsis
(American Society Of Plant Biologist, 2013-05)
Reactive oxygen species (ROS) can function as signaling molecules, regulating key aspects of plant development, or as toxic compounds leading to oxidative damage. In this article, we show that the regulation of ROS production ...
RAC1 activity and intracellular ROS modulate the migratory potential of MCF-7 cells through a NADPH oxidase and NF kappa B-dependent mechanism
(Elsevier Inc., 2008-08-18)
modulate the migratory properties in MCF-7 and T47D human mammary cell lines. We also described that the NFjB
pathway exerts a downstream control on the expression of the ROS-dependent cellular migratory potential. These ...
Contribution of NADPH oxidase to the establishment of hippocampal neuronal polarity in culture
(Company of Biologists Ltd., 2015)
Reactive oxygen species (ROS) produced by the NADPH oxidase (NOX) complex play
important physiological and pathological roles in neurotransmission and neurodegeneration,
respectively. However, the contribution of ROS to ...
Cisplatin inhibits testosterone synthesis by a mechanism that includes the action of reactive oxygen species (ROS) at the level of P450scc
(Elsevier Ireland, 2012-09)
Cisplatin (Cs) is a chemotherapeutic agent able to generate reactive oxygen species (ROS) which are linked to several side effects of the drug. Even when it is known that Cs produces Leydig cell dysfunction, it is unknown ...
Fluoride Increases Superoxide Production and Impairs the Respiratory Chain in ROS 17/2.8 Osteoblastic Cells
(Public Library of Science, 2014-06)
It is known that fluoride produces oxidative stress. Inflammation in bone tissue and an impairment of the respiratory chain of liver have been described in treatments with fluoride. Whether the impairment of the respiratory ...