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Structural abnormalities of the thalamus in juvenile myoclonic epilepsy

Universidade Estadual Paulista (Unesp); Universidade Estadual de Campinas (UNICAMP) (Academic Press Inc. Elsevier B.V., 2011-08-01)

Studies have suggested that the thalamus is a key structure in the pathophysiology of juvenile myoclonic epilepsy. The objective of the present investigation was to examine the thalami of patients with juvenile myoclonic ...

Neuropsychiatric profiles of patients with juvenile myoclonic epilepsy treated with valproate or topiramate

Araujo, GMD de; Pascalicchio, T. F.; Lin, K.; Sousa, P. S.; Yacubian, Elza Márcia Targas [UNIFESP] (Elsevier B.V., 2006-05-01)

In this cross-sectional study, the neuropsychiatric profiles of 42 patients with juvenile myoclonic epilepsy (JME) who were treated with valproate (VPA) or topiramate (TPM) in monotherapy were compared with the aim of ...

Cognitive performance in juvenile myoclonic epilepsy patients with specific endophenotypes

de Carvalho, Kelly Cristina [UNIFESP]; Pedroso Uchida, Carina Goncalves [UNIFESP]; Bittar Guaranha, Mirian Salvadori [UNIFESP]; Guilhoto, Laura Maria F. F. [UNIFESP]; Wolf, Peter; Targas Yacubian, Elza Marcia [UNIFESP] (W B Saunders Co Ltd, 2016)

Purpose: Juvenile myoclonic epilepsy (JME) is a heterogeneous syndrome in which seizures can be precipitated not only by non-specific factors, such as sleep deprivation and stress, but also by specific stimuli, such as ...

Psychiatric comorbidity in patients with two prototypes of focal versus generalized epilepsy syndromes

Araujo Filho, Gerardo Maria de [UNIFESP]; Mazetto, Lenon [UNIFESP]; Silva, Joyce Macedo da [UNIFESP]; Caboclo, Luís Otávio Sales Ferreira [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (W B Saunders Co Ltd, 2011-06-01)

The frequency of psychiatric disorders (PD) in a homogeneous series of patients with temporal lobe epilepsy with mesial temporal sclerosis (TLE-MTS) compared to patients with juvenile myoclonic epilepsy (JME) was evaluated, ...

Personality traits related to juvenile myoclonic epilepsy: MRI reveals prefrontal abnormalities through a voxel-based morphometry study

Araujo Filho, Gerardo Maria de [UNIFESP]; Jackowski, Andrea Parolin [UNIFESP]; Lin, Katia [UNIFESP]; Guaranha, Mirian S. B. [UNIFESP]; Guilhoto, Laura M. F. F. [UNIFESP]; Silva, Henrique Hattori da [UNIFESP]; Sales Ferreira Caboclo, Luis Otavio [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Bressan, Rodrigo Affonseca [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Elsevier B.V., 2009-06-01)

Studies involving juvenile myoclonic epilepsy (JME) patients have demonstrated an elevated prevalence of cluster B personality disorders (PD) characterized as emotional instability, immaturity, unsteadiness, lack of ...

Hippocampal atrophy and memory dysfunction in patients with juvenile myoclonic epilepsy

Lin, Katia [UNIFESP]; Araujo Filho, Gerardo Maria de [UNIFESP]; Pascalicchio, Tatiana Frascareli [UNIFESP]; Silva, Ivaldo [UNIFESP]; Silva Tudesco, Ivanda Souza [UNIFESP]; Bittar Guaranha, Mirian Salvadori [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Jackowski, Andrea Parolin [UNIFESP]; Targas Yacubian, Elza Marcia [UNIFESP] (Elsevier B.V., 2013-10-01)

Juvenile myoclonic epilepsy (JME) is a well-defined idiopathic generalized epilepsy (IGE) syndrome, being the most common IGE in adults and accounting for 5-11% of patients with epilepsy. While neuropsychological and ...

Expression of praxis induction on cortical excitability in juvenile myoclonic epilepsy

Vidal-Dourado, Marcos [UNIFESP]; Nunes, Karlo Faria [UNIFESP]; Bittar Guaranha, Mirian Salvadori [UNIFESP]; Pereira Giuliano, Lydia Maria [UNIFESP]; Targas Yacubian, Elza Marcia [UNIFESP]; Manzano, Gilberto Mastrocola [UNIFESP] (Elsevier Ireland Ltd, 2016)

Objective: This study aimed to evaluate the effects of praxis induction on sensorimotor cortical and transcallosal excitability in juvenile myoclonic epilepsy (JME). Methods: A total of 36 subjects (18-62 years) were ...