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The Unsolved Jigsaw Puzzle of the Immune Response in Chagas Disease
(Frontiers Research Foundation, 2018-07)
Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune response in a very complex and flowery manner. The history of host-parasite co-evolution has provided this protozoan with means ...
Redirection of the immune response to the functional catalytic domain of cruzipain improves protective immunity against Trypanosoma cruzi infection
(Oxford University Press, 2010-12)
Despite the strong immune responses elicited after natural infection with Trypanosoma cruzi or vaccination against it, parasite survival suggests that these responses are insufficient or inherently inadequate. T. cruzi ...
Probiotics and trained immunity
(MDPI AG, 2021-09-14)
The characteristics of innate immunity have recently been investigated in depth in several research articles, and original findings suggest that innate immunity also has a memory capacity, which has been named “trained ...
SLAM and CD31: signaling molecules involved in cytokine secretion during the development of innate and adaptive immune responses
(Elsevier, 2007-02)
Immune cells are modulated through the crosslinking of receptors named “immunoreceptors”. Ligation of immunoreceptors by their ligands induces a tyrosine-phosphorylation signal that is essential for cell activation or ...
Recent advances in non-specific immune memory against bovine tuberculosis
(Elsevier, 2021-04)
Bovine tuberculosis is an important worldwide disease mainly related to cattle, although it also affects other mammals, including humans. In recent years, there have been considerable advances in the knowledge of the immune ...
Galectin‐8 activates dendritic cells and stimulates antigen‐specific immune response elicitation
(2017-11)
Galectin‐8 (Gal‐8) is a mammalian β‐galactoside‐binding lectin, endowed with proinflammatory properties. Given its capacity to enhance antigen‐specific immune responses in vivo, we investigated whether Gal‐8 was also able ...
Evaluation of immune response, microbiota, and blood markers after probiotic bacteria administration in obese mice induced by a high-fat diet
(Elsevier Science Inc, 2014-11)
Objective: Obesity is associated with alterations in intestinal microbiota and immunity. The aim of this study was to determine the effect of probiotic Lactobacillus casei CRL 431 administration on intestinal and humoral ...
Glycobiology of immune responses
(John Wiley & Sons Inc, 2012-04-23)
Unlike their protein roommates and their nucleic acid cousins, carbohydrates remain an enigmatic arm of biology. The central reason for the difficulty in fully understanding how carbohydrate structure and biological function ...
A panoramic view of the immune response to Trypanosoma cruzi infection
(Springer, 2019)
Chagas disease is a complex disorder in which the immunological response developed by the host plays a fundamental role, not only in the clearance of the parasite but also in the inflammatory status observed in specific ...