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AT1 receptor blockade attenuates insulin resistance and myocardial remodeling in rats with diet-induced obesity
(Oxford University Press, 2012-08-01)
Immunolocalization of the insulin like growth factor-1 (IGF-1) and IGF-1 receptor (IGF-1R) in the ovary of the bitch
(Wiley-Blackwell, 2012-06-01)
Insulin Resistance in HIV-Patients: Causes and Consequences
(Frontiers Media Sa, 2018-09-05)
Here we review how immune activation and insulin resistance contribute to the metabolic alterations observed in HIV-infected patients, and how these alterations increase the risk of developing CVD. The introduction and ...
Toward an Explanation of the Genesis of Ketamine-Induced Perceptual Distortions and Hallucinatory States
(2003-12-01)
The NMDA receptor (NMDAR) channel has been proposed to function as a coincidence-detection mechanism for afferent and reentrant signals, supporting conscious perception, learning, and memory formation. In this paper we ...
Zinc supplementation for the prevention of type 2 diabetes mellitus in adults with insulin resistance
(Wiley-Blackwell, 2015-01-01)
BackgroundDiabetes is associated with long-term damage, dysfunction and failure of various organs, especially the eyes, kidneys, nerves, heart and blood vessels. The risk of developing type 2 diabetes increases with age, ...
Rock protein as cardiac hypertrophy modulator in obesity and physical exercise
(2020-08-01)
Obesity and cardiovascular diseases are worldwide public health issues. In this review, we discussed the participation of ROCK protein in cardiac hypertrophy, mainly through the modulation of leptin and insulin signaling ...
Involvement of the atrial natriuretic peptide in cardiovascular pathophysiology and its relationship with exercise
(2012-02-08)
In this minireview we describe the involvement of the atrial natriuretic peptide (ANP) in cardiovascular pathophysiology and exercise. The ANP has a broad homeostatic role and exerts complex effects on the cardio-circulatory ...
Maternal protein malnutrition: Effects on prostate development and adult disease
(2018-08-01)
Well-controlled intrauterine development is an essential condition for many aspects of normal adult physiology and health. This process is disrupted by poor maternal nutrition status during pregnancy. Indeed, physiological ...
Role of neuronal guidance cues in the pathophysiology of obesity: A peripher-al and central overview
(2021-06-01)
Obesity is associated with an exacerbated synthesis and secretion of several molecules, which culmi-nates in chronic low-grade inflammation and insulin resistance. Such conditions affect molecular and physiolog-ical responses ...