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Estudos estruturais e das interações com membranas de peptídeos antimocrobianos por RMN em solução e em fase sólida: análise conformacional e cálculos ab-initio de tensores de blindagem
(Universidade Federal de Minas GeraisUFMG, 2008-08-18)
Phylloseptins are antimicrobial peptides of 19 to 20 residues which are found in the skin secretions of the Phyllomedusa frogs that inhabit the tropical forests of South and Central Americas. The focus of this PhD thesis ...
Análise estrutural e topológica de peptídeos bioativos em meios biomiméticos de membranas
(Universidade Federal de Minas GeraisUFMG, 2012-02-24)
This work consists of studies on the structure and interactions with membrane-mimetic media of the antimicrobial peptides distinctin, an heterodimer composed of two peptide chains (chain 1 and chain 2) covalently bonded ...
Modelagem computacional de sistemas de liberação controlada de complexos de platina(II) com atividade antitumoral formados por nanocompostos de carbono
(Universidade Federal de Minas GeraisUFMG, 2015-03-31)
In this work, a quantum chemical investigation was performed to study the inclusion complexes formation between a carbon nanohorn (NH) and nanotube (CNT) structures with cisplatin (cDDP) and its derivative dinuclear ...