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Immune mediators of pathology in neurobrucellosis: from blood to central nervous system
(Elsevier, 2019-07)
Neurobrucellosis, which is the most morbid form of brucellosis disease, presents with inflammatory signs and symptoms. Recent experimental evidence clearly indicates that deregulation of astrocytes and microglia caused by ...
Distribution and characterization of corazonin in the central nervous system of Triatoma infestans (Insecta: Heteroptera)
(Elsevier Science, 2011-03)
The distribution of corazonin in the central nervous system of the heteropteran insect Triatoma infestans was studied by immunohistochemistry. The presence of corazonin isoforms was investigated using MALDI-TOF mass ...
Are Glial Cells Critical Participants in Brain Development, Function, and Disease?
(OMINCS, 2012-09)
Recently, an increasing number of studies have implicated a third element in plasticity; the perisynaptic glial cell. Originally glial cells were thought to be important for metabolic maintenance and support of Central The ...
Histone methylations in the developing central nervous system and in neural tube defects
(De Gruyter, 2018-05)
Understanding central nervous system genesis is of crucial relevance to decode different human diseases such as microcephaly or neural tube defects, which arise from incorrect developmental processes. Epigenetic mechanisms ...
Severe Acute Respiratory Syndrome Coronavirus 2 Impact on the Central Nervous System: Are Astrocytes and Microglia Main Players or Merely Bystanders?
(SAGE Publications, 2020-09)
With confirmed coronavirus disease 2019 (COVID-19) cases surpassing the 18 million mark around the globe, there is an imperative need to gain comprehensive understanding of severe acute respiratory syndrome coronavirus 2 ...
Progesterone for the treatment of central nervous system disorders: the many signaling roads for a single molecule
(Chinese Association of Rehabilitation Medicine, 2020-04)
Central nervous system (CNS) injuries and neurodegenerative diseases show a broad spectrum of common pathophysiological processes, including oxidative stress, neuroinflammation, excitotoxicity, demyelination and neurotransmission ...
Signaling within the pineal gland: A parallelism with the central nervous system
(Academic Press Ltd - Elsevier Science Ltd, 2018-12)
The pineal gland (PG) derives from the neural tube, like the rest of the central nervous system (CNS). The PG is specialized in synthesizing and secreting melatonin in a circadian fashion. The nocturnal elevation of melatonin ...
Central Nervous System Targets and Routes for SARS-CoV-2: Current Views and New Hypotheses
(American Chemical Society Inc, 2020-09)
As the coronavirus disease 2019 (COVID-19) pandemic unfolds, neurological signs and symptoms reflect the involvement of targets beyond the primary lung effects. The etiological agent of COVID-19, the severe acute respiratory ...
Pharmacology and toxicology of polyphenols with potential as neurotropic agents in non-communicable diseases
(Bentham Science Publishers, 2018-03)
The central nervous system (CNS) is involved in organic integration. Nervousmodulation via bioactive compounds can modify metabolism in order to prevent systemic noncommunicablediseases (NCDs). Concerning this, plant ...