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Osteogenesis-inducing calcium phosphate nanoparticle precursors applied to titanium surfaces
(2013-05-20)
This study investigated the effects of the morphology and physicochemical properties of calcium phosphate (CaP) nanoparticles on osteogenesis. Two types of CaP nanoparticles were compared, namely amorphous calcium phosphate ...
A gene signature in histologically normal surgical margins is predictive of oral carcinoma recurrence
(Biomed Central Ltd., 2011-10-11)
Background: Oral Squamous Cell Carcinoma (OSCC) is a major cause of cancer death worldwide, which is mainly due to recurrence leading to treatment failure and patient death. Histological status of surgical margins is a ...
Fibrosis-related gene expression in the prostate is modulated by doxazosin treatment
(Pergamon-Elsevier B.V. Ltd, 2012-12-17)
Aims: To gain new insights into the molecular mechanisms of action of doxazosin, we investigated the prostatic stroma ultrastructure and the expression of genes involved with fibrosis, such as collagen type I and III (COL1A1 ...
Collagen XVIII and LOXL-4 polymorphisms in women with and without advanced pelvic organ prolapse
(Springer London Ltd, 2018)
Introduction and hypothesis We verified the presence of single nucleotide polymorphisms (SNP) rs2236479 of the collagen 18 (COL18A1) and rs2862296 of the lysyl oxidase-like 4 (LOXL-4) genes and the association with pelvic ...
Effect of low-level laser irradiation on odontoblast-like cells
(Astro Ltd, 2008-09-01)
Low-level laser therapy (LLLT), also referred to as therapeutic laser, has been recommended for a wide array of clinical procedures, among which the treatment of dentinal hypersensitivity. However, the mechanism that guides ...
Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice
(Oxford Univ Press Inc, 2016)
Millions of levothyroxine-treated hypothyroid patients complain of impaired cognition despite normal TSH serum levels. This could reflect abnormalities in the type 2 deiodinase (D2)-mediated T-4-to-T-3 conversion, given ...
Evaluation of Demographic, Clinical Characteristics, and Genetic Polymorphism as Risk Factors for Pelvic Organ Prolapse in Brazilian Women
(Wiley-Blackwell, 2011-01-01)
Objective: Verify the association between genital prolapse, other risk factors and a polymorphism in exon 31 of the collagen III-a1 gene (COL3A1). Setting: the etiology of genital prolapse is multifactorial, and genetic ...