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Nitazoxanide in the treatment of Ascaris lumbricoides in a rural zone of Colima, Mexico
(2011)
Functionalized carbene ligands: Increasing the steric bulk of R1 on 1 from H to tBu results in lengthening of the M-N bond (by up to 9 %), lowered activation energy for chelate opening (cf. 2) by 17 kcal mol -1, and improved ...
Hepatic phosphorylase b kinase deficiency with normal enzyme activity in leukocytes
(1988)
[No abstract available]
Absolute quantitation of different genotypes of hepatitis C virus RNA in clinical samples by a modified real-time PCR method
(2011)
Background: Our aim was to develop a quantitative real-time polymerase chain reaction (qPCR) assay for the quantitation of hepatitis C virus (HCV) RNA samples from patients infected with different HCV genotypes. Methods: ...
Discovery of potent positive allosteric modulators of the α3β2 nicotinic acetylcholine receptor by a chemical space walk in chembl
(2014)
While a plethora of ligands are known for the well studied α7 and α4β2 nicotinic acetylcholine receptor (nAChR), only very few ligands address the related α3β2 nAChR expressed in the central nervous system and at the ...
Discovery of potent positive allosteric modulators of the ?3?2 nicotinic acetylcholine receptor by a chemical space walk in chembl
(2014)
While a plethora of ligands are known for the well studied ?7 and ?4?2 nicotinic acetylcholine receptor (nAChR), only very few ligands address the related ?3?2 nAChR expressed in the central nervous system and at the ...
Use of proteomic analysis tools to identify HCV-proteins down-regulated by acetylsalicylic acid
(2013)
Background and aim. Acetylsalicylic acid (ASA) has been shown to downregulate HCV expression; however, the involved mechanisms are unknown. We used proteomic analysis to compare protein expression profiles between human ...
Acetylsalicylic acid inhibits hepatitis C virus RNA and protein expression through cyclooxygenase 2 signaling pathways
(2008)
It has been reported that salicylates (sodium salicylate and aspirin) inhibit the replication of flaviviruses, such as Japanese encephalitis virus and dengue virus. Therefore, we considered it important to test whether ...
Cu/Zn superoxide dismutase (SOD1) induction is implicated in the antioxidative and antiviral activity of acetylsalicylic acid in HCV-expressing cells
(2012)
We evaluated the participation of oxidative stress in the negative regulation of hepatitis C virus (HCV)- RNA induced by acetylsalicylic acid (ASA). We used the HCV subgenomic replicon cell system that stably expresses ...
Cu/Zn superoxide dismutase (SOD1) induction is implicated in the antioxidative and antiviral activity of acetylsalicylic acid in HCV-expressing cells
(2012)
We evaluated the participation of oxidative stress in the negative regulation of hepatitis C virus (HCV)- RNA induced by acetylsalicylic acid (ASA). We used the HCV subgenomic replicon cell system that stably expresses ...