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Análisis predictivo de potenciales epítopes protectores de Salmonella infantis a través de herramientas inmuno-bioinformáticas
(Universidad Peruana Cayetano HerediaPE, 2021)
In recent years, our country has been reporting the presence and increase of multidrug resistant strains of Salmonella enterica subspecies enterica serotype Infantis (Salmonella Infantis) in chickens. This serotype is ...
Improved peptide-MHC class II interaction prediction through integration of eluted ligand and peptide affinity data
(Springer, 2019-05)
Major histocompatibility complex (MHC) class II antigen presentation is a key component in eliciting a CD4+ T cell response. Precise prediction of peptide-MHC (pMHC) interactions has thus become a cornerstone in defining ...
Dataset size and composition impact the reliability of performance benchmarks for peptide-MHC binding predictions
(BioMed Central, 2014-07)
BACKGROUND: It is important to accurately determine the performance of peptide:MHC binding predictions, as this enables users to compare and choose between different prediction methods and provides estimates of the expected ...
Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol
(Academic Press Inc, 1999-02-24)
In this study we investigated the fate of a class of proteasome-generated oligopeptides, exposing them to the crude cytosol of macrophages or to the purified recombinant thimet oligopeptidase. Among the proteasome products ...
Plasmodium vivax Pv12 B-cell epitopes and HLA-DRβ1-dependent T-cell epitopes in vitro antigenicity
(2018)
Malaria is an infectious disease caused by parasites from the genus Plasmodium (P. falciparum and P. vivax are responsible for 90% of all clinical cases); it is widely distributed throughout the world’s tropical and ...