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Directed assembly of active colloidal molecules
(Institute of Physics Publishing, 2019)
Having a production line for microrobots is fundamental to their widespread application in many areas. Thanks to their flexibility, active colloidal molecules with dynamic function are a promising model for microrobots. ...
The modulatory role of sulfated and non-sulfated small molecule heparan sulfate-glycomimetics in endothelial dysfunction: absolute structural clarification, molecular docking and simulated dynamics, SAR analyses and ADMET studies
(Royal Soc Chemistry, 2021-04-23)
The conceptual technology of small molecule glycomimetics, exemplified by compounds C1-4, has shown promising protective effects against lipid-induced endothelial dysfunction, restorative effects on diabetic endothelial ...
Reprogramação de astrócitos corticais em neurônios utilizando coquetel de pequenas moléculas
(Universidade Federal do Rio Grande do NorteBrasilUFRNBiomedicina, 2016-11-02)
Recently, many techniques have been described to generate neurons that could be used in cell-based therapies to neurodegenerative diseases or acute central nervous system injuries. One of such techniques is the lineage ...
On the interaction of small molecules with hemoproteins: Sperm whale myoglobin
(1985-06-01)
The spin label TEMPO does not show a binding to myoglobin molecule in solution. This is probably due to the fact that this protein does not have a hydrophobic pocket large enough to accommodate the TEMPO molecule. In the ...
On the interaction of small molecules with hemoproteins: Sperm whale myoglobin
(1985-06-01)
The spin label TEMPO does not show a binding to myoglobin molecule in solution. This is probably due to the fact that this protein does not have a hydrophobic pocket large enough to accommodate the TEMPO molecule. In the ...
Recent advances in the discovery of small molecules targeting glioblastoma
(2019-02-15)
Glioblastoma (GBM) is one of the most common central nervous system cancers. It is characterized as a fast-growing tumor that arises from multiple cell types with neural stem-cell-like properties. Additionally, GBM tumors ...
Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles
(Elsevier, 2017)
Buccal delivery of macromolecules (biologics) sets a great challenge for researchers. Although several niche small molecule products have been approved as simple sprays, tablets and oral films, it is not simply a case of ...
Theory of scanning tunneling microscopy of adsorbed molecules on metallic surfaces for nearly localized atomic states
(American Physical Society, 2011-04)
We consider a Hubbard-Anderson model which describes localized orbitals in five different sites hybridized both among themselves and with a continuum of extended states. A square planar geometry with an atom at the center ...