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Downhill Running-based Overtraining Protocol Improves Hepatic Insulin Signaling Pathway Without Concomitant Decrease Of Inflammatory Proteins
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2015)
Combined docosahexaenoic acid and thyroid hormone supplementation as a protocol supporting energy supply to precondition and afford protection against metabolic stress situations
(2019)
Liver preconditioning (PC) refers to the development of an enhanced tolerance to injuring stimuli. For example, the protection from ischemia-reperfusion (IR) in the liver that is obtained by previous maneuvers triggering ...
Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet-induced obese mice, independently of weight loss
(WILEY-BLACKWELLMALDEN, 2012-07)
Hepatic insulin resistance is the major contributor to fasting hyperglycemia in type 2 diabetes. The protein kinase Akt plays a central role in the suppression of gluconeogenesis involving forkhead box O1 (Foxo1) and ...
Bradykinin inhibits hepatic gluconeogenesis in obese mice
(Nature Publishing Group, 2012-10-01)
The kallikrein-kinin system (KKS) has been previously linked to glucose homeostasis. in isolated muscle or fat cells, acute bradykinin (BK) stimulation was shown to improve insulin action and increase glucose uptake by ...
Eicosapentaenoic acid promotes mitochondrial biogenesis and beige-like features in subcutaneous adipocytes from overweight subjects
(ELSEVIER SCIENCE INC, 2016)
Eicosapentaenoic acid (EPA), a n-3 long-chain polyunsaturated fatty acid, has been reported to have beneficial effects in obesity-associated metabolic disorders. The objective of the present study was to determine the ...
Avaliação da trigonelina e curcumina, isoladas ou co-administradas em iogurte, em modelo experimental de obesidade e resistência à insulina
(Universidade Estadual Paulista (Unesp), 2019-05-31)
Introdução: Ativos naturais têm sido estudados por suas ações antioxidantes, anti-inflamamatórias e antiglicação, que podem ser interessantes para prevenir/atenuar as complicações da obesidade e do diabetes mellitus (DM). ...
The Role of Lipotoxicity in Smoke Cardiomyopathy
(Public Library Science, 2015)
A influência da abreviação do jejum pré-operatório na sensação de sede e na resistência insulínica de pacientes com fratura de fêmur proximal.
(Universidade Estadual Paulista (Unesp), 2020-12-16)
Introdução: A fratura de fêmur proximal (FFP) em idosos é um problema de saúde pública. Associa-se à elevada morbimortalidade, queda na qualidade de vida e aumento dos custos. Do ponto de vista fisiopatológico o jejum ...